
Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences
- English
- PDF
- Available on iOS & Android
Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences
About this book
A practical guide to the use of basic principles of experimental design and statistical analysis in pharmacology
Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences provides clear instructions on applying statistical analysis techniques to pharmacological data. Written by an experimental pharmacologist with decades of experience teaching statistics and designing preclinical experiments, this reader-friendly volume explains the variety of statistical tests that researchers require to analyze data and draw correct conclusions.
Detailed, yet accessible, chapters explain how to determine the appropriate statistical tool for a particular type of data, run the statistical test, and analyze and interpret the results. By first introducing basic principles of experimental design and statistical analysis, the author then guides readers through descriptive and inferential statistics, analysis of variance, correlation and regression analysis, general linear modelling, and more. Lastly, throughout the textbook are numerous examples from molecular, cellular, in vitro, and in vivo pharmacology which highlight the importance of rigorous statistical analysis in real-world pharmacological and biomedical research.
This textbook also:
- Describes the rigorous statistical approach needed for publication in scientific journals
- Covers a wide range of statistical concepts and methods, such as standard normal distribution, data confidence intervals, and post hoc and a priori analysis
- Discusses practical aspects of data collection, identification, and presentation
- Features images of the output from common statistical packages, including GraphPad Prism, Invivo Stat, MiniTab and SPSS
Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences is an invaluable reference and guide for undergraduate and graduate students, post-doctoral researchers, and lecturers in pharmacology and allied subjects in the life sciences.
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Information
Table of contents
- Cover
- Title Page
- Copyright Page
- Biography
- Contents
- Acknowledgements
- Foreword
- Chapter 1 Introduction
- Chapter 2 So, what are data?
- Chapter 3 Numbers; counting and measuring, precision, and accuracy
- Chapter 4 Data collection: sampling and populations, different types of data, data distributions
- Chapter 5 Descriptive statistics; measures to describe and summarise data sets
- Chapter 6 Testing for normality and transforming skewed data sets
- Chapter 7 The Standard Normal Distribution
- Chapter 8 Non-parametric descriptive statistics
- Chapter 9 Summary of descriptive statistics: so, what values may I use to describe my data?
- Chapter 10 Introduction to inferential statistics
- Chapter 11 Comparing two sets of data – Independent t-test
- Chapter 12 Comparing two sets of data – Paired t-test
- Chapter 13 Comparing two sets of data – independent non-parametric data
- Chapter 14 Comparing two sets of data – paired non-parametric data
- Chapter 15 Parametric one-way analysis of variance
- Chapter 16 Repeated measure analysis of variance
- Chapter 17 Complex Analysis of Variance Models
- Chapter 18 Non-parametric ANOVA
- Chapter 19 Correlation analysis
- Chapter 20 Regression analysis
- Chapter 21 Chi-square analysis
- Chapter 22 Confidence intervals
- Chapter 23 Permutation test of exact inference
- Chapter 24 General Linear Model
- Appendix A: Data distribution: probability mass function and probability density functions
- Appendix B: Standard normal probabilities
- Appendix C: Critical values of the t-distribution
- Appendix D: Critical values of the Mann–Whitney U-statistic
- Appendix E: Critical values of the F distribution
- Appendix F: Critical values of chi-square distribution
- Appendix G: Critical z values for multiple non-parametric pairwise comparisons
- Appendix H: Critical values of correlation coefficients
- Index
- EULA