This second volume chronicles the later stages of the outbreak of SARS-Cov-2 (COVID-19) and delineates the role of several disciplines in therapeutic and control measures highliting the response from specific coutries of note and efforts to repurpose and produce new therapeutics and vaccines. By addressing considerations of efficacy and safety of drugs and chemicals used to combat COVID-19, virtually in real-time, this book documents and highlights the advances in science and place the toxicology, pharmaceutical science, public health and medical community in a better position to advise in future epidemics.

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Yes, you can access The Coronavirus Pandemic and the Future by Michael D Waters, Alok Dhawan, Tim Marrs, Diana Anderson, Stafford Warren, Claude L Hughes, Michael D Waters,Alok Dhawan,Tim Marrs,Diana Anderson,Stafford Warren,Claude L Hughes in PDF and/or ePUB format, as well as other popular books in Medicine & Infectious Diseases. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Royal Society of Chemistry

Year

2022

eBook ISBN

9781839166846

Edition

Topic

Medicine

Subtopic

Infectious Diseases

Volume 1 The Coronavirus Pandemic and the Future: Virology, Epidemiology, Translational Toxicology and Therapeutics

Chapter 1 What We Know About the Life-threatening Novel Human Coronavirus 1

Claude Hughes, Arul Narayanaswamy, Balachandar Vellingiri, Dhivya Venkatesan, Stafford Warren and Michael Waters

1.1Introduction

1.2The Chronology of the Outbreak

1.3Initial Transmission

1.3.1Worldwide Spread of the Virus

1.4SARS-CoV-2 and Its Etiology

1.5Classification and Grouping

1.5.1Alpha-CoVs

1.5.2Beta-CoVs

1.5.3Gamma-CoVs

1.5.4Delta-CoVs

1.6Epidemiological History of Human Coronaviruses

1.6.1Severe Acute Respiratory Syndrome

1.6.2Middle East Respiratory Syndrome

1.7Introductory Virology and Pathophysiology of SARS-CoV-2

1.7.1Viral Genome

1.7.2Interaction of the Spike and Receptor for Entry

1.7.3Genomic Differences

1.7.4Pathophysiology

1.8Executive Summary and Conclusions

List of Abbreviations

Acknowledgements

References

Chapter 2Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2): Structure, Lifecycle, and Replication Machinery

Arghadip Samaddar and Vijaya Lakshmi Nag

2.1Introduction

2.2Classification of Coronaviruses

2.3Genomic Structure of SARS-CoV-2

2.4Life Cycle of SARS-CoV-2

2.4.1Attachment and Entry

2.4.2Replicase Protein Expression

2.4.3Replication and Transcription

2.4.4Assembly and Release

2.5SARS-CoV-2 RNA Replication Machinery

References

Chapter 3Accumulated Epidemiological Lessons and China's COVID-19 Response

Chao Xie and Liangmin Gao

3.1Introduction

3.2Accumulated Lessons from China's Response to SARS in 2003

3.3Epidemiologicial Perspective on China's COVID-19 Response

3.4China's Control and Prevention Measures in COVID-19

3.4.1Mask-wearing and its Comforting Effect

3.4.2Epidemiological Source-tracking and Slow-down of Community Transmission

3.5Comparing China's Response Against SARS and COVID-19

3.6Concluding Remarks

3.7Executive Summary

References

Chapter 4Clinical Presentation, Pathophysiology and Histopathology

Claude Hughes, Iyer Mahalaxmi, Nachimuthu Senthil Kumar, Suresh Selvapuram Sudalaimuthu Raja, Raviminickam Thangarasu, Stafford Warren and Michael Waters

4.1Introduction

4.2The Distinct Clinical Trajectory and Disease Spectrum of COVID-19

4.3A Novel Application of Smartphone Technology

4.4COVID-19 and Comorbidities in Severe Cases

4.5ARDS and its Sequelae in COVID-19

4.5.1ARDS in COVID-19

4.5.2Sepsis

4.5.3Septic Shock

4.6Pathophysiology

4.6.1Mechanism of SARS-Cov-2 Invasion into Host Cells

4.7Histopathology and Disease Manifestations: Introduction

4.7.1Histopathology

4.7.2Pulmonary Manifestations

4.7.3Cardiovascular Manifestations

4.7.4Gastrointestinal Manifestations

4.7.5Renal Manifestations

4.7.6Neurological Manifestations

4.7.7Musculocutaneous Manifestations

4.7.8Hematological Manifestations

4.8Executive Summary

Acknowledgemen...

Cover
Title
Copyright
Dedication
Foreword
Preface
Volume 1-Contents
Volume 2-Contents
Chapter 1 In Silico Approaches for Drug Repurposing for SARS-CoV-2 Infection
Chapter 2 Vaccination and Vaccines for COVID-19
Chapter 3 Understanding the Emergence of SARS-CoV-2 Viral Variants From a Genomic Perspective
Chapter 4 Susceptibility and Spread of SARS-CoV-2 in Animals
Chapter 5 Profiling Some Plant-based Immunomodulatory Bioactive Compounds for COVID-19 Prophylaxis and Treatment Based on Indian Traditional Medicine
Chapter 6 The Potential Therapeutic Effects of Natural Products, Herbs, and Mushrooms Against COVID-19
Chapter 7 Application of Chinese Herbal Medicine in COVID-19
Chapter 8 COVID-19 Interventional and Therapeutic Clinical Trials: Small Molecules, Interactions, Outcomes and Opportunities
Chapter 9 A Trend Analysis of the COVID-19 Pandemic in Turkey and in the Indian State of Kerala
Chapter 10 The Swedish Approach to COVID-19
Chapter 11 New Zealand's Response to the First Wave of COVID-19
Chapter 12 Significant SARS-CoV-2 Variants Circulating Around the World: Origin, Spread and Phylodynamics
Chapter 13 Survival of SARS-CoV-2 Outside the Body and Methods of Disinfection
Chapter 14 US Regulatory Approaches to Disinfectants for Coronavirus
Chapter 15 Diagnostic Strategies for Early and Point-of-Care Detection of COVID-19 in Clinical and Personalized Settings
Chapter 16 Human Resource Management, Preparedness, and Outcomes
Chapter 17 The Role of Telehealth During the COVID-19 Pandemic
Chapter 18 Medical Education During the COVID Pandemic: Challenges and Solutions
Chapter 19 Containment Strategies to Prevent Spread in Different Societies and Cultures
Chapter 20 Effective Health Education, Patient Education and Health Behaviour Change
Chapter 21 Strengthening the Biological and Toxin Weapons Convention After COVID-19: Reaching Agreement on a Code of Conduct and Biological Security Education at the 2021 9th Review Conference
Chapter 22 Covid-19 Prevention
Chapter 23 Human Responses to Pandemics in History and Medico-anthropological Correlates
Chapter 24 The COVID-19 Pandemic – Global Lessons for the Future
Subject Index

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