Bioprocessing of Viral Vaccines
eBook - ePub

Bioprocessing of Viral Vaccines

  1. 320 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Bioprocessing of Viral Vaccines

About this book

This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines. Bioprocessing of Viral Vaccines, will provide an overview of the advanced strategies needed to respond to the challenges of new and established viral infection diseases. The first few chapters cover the basics of virology and immunology as essential concepts to understand the function and design of viral vaccines. The core of the content is dedicated to process development, including upstream processing and cell culture of viral vaccines, downstream processing, and extensive analytical technologies specific to viral vaccines. Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are also introduced in the context of vaccine manufacturing. The case studies included cover inactivated, attenuated vaccines exemplified by influenza vaccines, sub-unit vaccines exemplified by Virus Like Particles (VLPs: HPV vaccines) and sub-unit vaccines (Flublock), vectored vaccines: adenoviruses and Vesicular stomatitis Virus (VSV) vectored vaccines, genomic vaccines (DNA and mRNA) vaccines as developed for COVID-19 response in particular and a review of COVID-19 vaccines approved or in advanced clinical trials. This book is aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines.

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Yes, you can access Bioprocessing of Viral Vaccines by Amine Kamen,Laura Cervera in PDF and/or ePUB format, as well as other popular books in Medicine & Immunology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2022
eBook ISBN
9781000643053
Edition
1
Topic
Medicine
Subtopic
Immunology

Table of contents

  1. Cover
  2. Half Title
  3. Title Page
  4. Copyright Page
  5. Contents
  6. Editors
  7. List of abbreviations
  8. Chapter 1 Bioprocessing of viral vaccines–Introduction
  9. Chapter 2 Introduction to virology
  10. Chapter 3 Introduction to basic immunology and vaccine design
  11. Chapter 4 Cell lines for vaccine production
  12. Chapter 5 Upstream processing for viral vaccines–General aspects
  13. Chapter 6 Upstream processing for viral vaccines-Process intensification
  14. Chapter 7 Downstream processing of viral-based vaccines
  15. Chapter 8 Analytics and virus production processes
  16. Chapter 9 Manufacturing of seasonal and pandemic influenza vaccines–A case study
  17. Chapter 10 Recombinant vaccines: Gag-based VLPs
  18. Chapter 11 Vectored vaccines
  19. Chapter 12 Design and production of vaccines against COVID-19 using established vaccine platforms
  20. Index