Physiological Consequences of Brain Insulin Action
eBook - ePub

Physiological Consequences of Brain Insulin Action

André Kleinridders, André Kleinridders

  1. 244 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Physiological Consequences of Brain Insulin Action

André Kleinridders, André Kleinridders

Book details
Table of contents
Citations

About This Book

The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well as cognition. This is partially achieved by modulating several types of brain cell populations including those relevant to satiety and reward. Importantly, brains of Alzheimer´s disease patients exhibit a signature of brain insulin resistance with perturbed brain metabolism. This book will cover the basics of insulin signaling in the brain and will describe concepts of insulin resistance, a feature of type 2 diabetes. Moreover insulin´s effect on cognitive function will be pointed out and the association between brain insulin resistance and neurodegenerative diseases discussed. Additionally, potential behavioral and pharmacological concepts which can affect brain insulin signaling will be summarized.

Key Features:



  • Summarizes insulin and the closely related IGF-1 receptor signaling



  • Depicts concepts of insulin resistance



  • Highlights the importance of conserved brain insulin signaling for brain function, metabolism, and behavior



  • Describes potential behavioral and pharmacological approaches to support brain insulin signaling

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Yes, you can access Physiological Consequences of Brain Insulin Action by André Kleinridders, André Kleinridders in PDF and/or ePUB format, as well as other popular books in Médecine & Endocrinologie et métabolisme. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2022
ISBN
9781000643206
Edition
1
Topic
Médecine
Subtopic
Endocrinologie et métabolisme

Table of contents

  1. Cover
  2. Half Title
  3. Series Page
  4. Title Page
  5. Copyright Page
  6. Table of Contents
  7. Series Preface
  8. Preface
  9. Acknowledgements
  10. Editor
  11. Contributors
  12. Abbreviations
  13. 1 • Molecular Mechanisms of Brain Insulin Signaling
  14. 2 • Insulin/IGF Signaling in Early Brain Development
  15. 3 • Insulin Signaling Modulates Neuronal Metabolism
  16. 4 • Regulation of Glial Function by Insulin Peptides
  17. 5 • Neuroendocrine Interactions in the Control of Glucose- and Energy Homeostasis
  18. 6 • Hypothalamic Neuronal Circuits Are Modulated by Insulin and Impact Metabolism
  19. 7 • Insulin and Brain Reward Systems
  20. 8 • The Impact of Insulin on Brain Serotonergic System: Consequences on Diabetes-Associated Mood Disorders
  21. 9 • Organ Cross-Talk Regulates (Brain) Insulin Action
  22. 10 • Insulin Resistance as a Risk Factor for Alzheimer’s Disease
  23. 11 • Brain Insulin Action in the Control of Metabolism in Humans
  24. 12 • Impact of Dietary and Exercise Interventions on Brain Insulin Action and Brain Function
  25. 13 • Pharmacological and Surgical Interventions to Improve Brain Insulin Resistance
  26. Index