Uncertainties in External Beam Radiation Therapy

Monograph No. 35

Jatinder R. Palta, T. Rock Mackie

• Publisher: Medical Physics Publishing
• Year: 2011
• eBook ISBN:
  9781936366538
• Print ISBN:
  9781930524521

This text was developed for the AAPM's 2011 summer school in Burnaby, British Columbia. The focus of the summer school was to (a) understand the potential sources of dosimetric uncertainties in radiotherapy, (b) evaluate the impact of these uncertainties on the accuracy and conformity of dose delivered to patients, (c) understand strategies for mitigating these uncertainties, and (d) understand the impact of these uncertainties on QA/QM. The images in the eBook are in color.

Table of contents

• CHAPTER 1--Dosimetric Uncertainties and Normal Tissue Tolerance
• CHAPTER 2--Biologically Conformal Radiotherapy: Targeting Based on Biological Imaging
• CHAPTER 3--Immobilization from Rigid to Non-Rigid
• CHAPTER 4--Uncertainties in Reference Dosimetry
• CHAPTER 5--Treatment Planning Dose Computation
• CHAPTER 6--Uncertainties in the Evaluation of Treatment Plans
• CHAPTER 7--Motion Management Strategies
• CHAPTER 8--Margins and Margin Recipes
• CHAPTER 9--Robust Optimization
• CHAPTER 10--Limits of Precision and Accuracy of Radiation Delivery Systems
• CHAPTER 11--Patient Setup Uncertainties (Interfraction)
• CHAPTER 12--Developing a Rationale for Tolerance Values and Action Levels for the Performance of Planning and Delivery Systems
• CHAPTER 13--Model Planning and Delivery Uncertainties
• CHAPTER 14--Image Guidance To Reduce Setup Error
• CHAPTER 15--In Vivo Dosimetry for Patients Undergoing External Beam Radiation Therapy
• CHAPTER 16--Dealing with Intrafraction Motion
• CHAPTER 17--Uncertainties in Deformable Registration
• CHAPTER 18--Uncertainties and Limitations in Adaptive Radiotherapy
• CHAPTER 19--Challenges of Image-based Response Assessment in Radiation Therapy
• CHAPTER 20--Current and Future Quality Practice
• CHAPTER 21--New Paradigms for Quality Management in Radiation Therapy
• CHAPTER 22--Human Performance and the Quality and Safety of Radiation Therapy
• CHAPTER 23--Summary of the Reports by the International Commission on Radiation Units and Measurements on Prescribing, Reporting, and Recording in Radiation Therapy
• CHAPTER 24--Uncertainties in Selection and Delineation of Target Volumes and Organs at Risk in Head and Neck Tumors
• CHAPTER 25--Thorax
• CHAPTER 26--Assessment and Management of Uncertainties: Overview of Prostate Cancer Radiotherapy
• CHAPTER 27--Perspectives on Technology and Practices for Assuring Quality in Radiation Therapy Delivery