Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 3
eBook - PDF

Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 3

  1. 401 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 3

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Information

Publisher
American Chemical Society
Year
2020
eBook ISBN
9780841298637
Print ISBN
9780841298637

Table of contents

  1. Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 3
  2. ACS Symposium Series1369
  3. Foreword
  4. Preface
  5. Discovery and Chemical Development of the Use-Dependent Sodium Channel Blocker Vixotrigine for the Treatment of Pain
  6. The Discovery and Chemical Development of BMS-919373: A Selective IKur Inhibitor for the Potential Treatment of Atrial Fibrillation
  7. Discovery and Development of Omecamtiv Mecarbil: A Novel Cardiac Myosin Activator for the Potential Treatment of Systolic Heart Failure
  8. Identification and Development of AMG 986: A Potent and Efficacious APJ Agonist for the Treatment of Heart Failure
  9. Melflufen: A Journey from Discovery to Multi-Kilogram Production
  10. Discovery and Chemical Development of S 44563, a Dual Bcl-2/Bcl-xL Inhibitor
  11. Discovery and Chemical Development of Tesirine: An Antitumor Pyrrolobenzodiazepine Antibody-Drug Conjugate Drug-Linker
  12. Discovery and Chemical Development of Relebactam: A Potent β-Lactamase Inhibitor in Combination with PrimaxinŽ for the Treatment of Serious and Antibiotic-Resistant Bacterial Infections
  13. Discovery and Chemical Development of Grazoprevir: An HCV NS3/4a Protease Inhibitor for the Treatment of the Hepatitis C Virus Infection
  14. Discovery and Process Development of BIIB068: A Reversible Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Autoimmune Diseases
  15. Discovery and Commercial Development of Cholesteryl Transfer Protein Inhibitor Evacetrapib
  16. Editors’ Biographies
  17. Indexes
  18. Author Index
  19. Subject Index
  20. Preface
  21. Discovery and Chemical Development of the Use-Dependent Sodium Channel Blocker Vixotrigine for the Treatment of Pain
  22. References and Notes
  23. The Discovery and Chemical Development of BMS-919373: A Selective IKur Inhibitor for the Potential Treatment of Atrial Fibrillation
  24. Discovery and Development of Omecamtiv Mecarbil: A Novel Cardiac Myosin Activator for the Potential Treatment of Systolic Heart Failure
  25. Identification and Development of AMG 986: A Potent and Efficacious APJ Agonist for the Treatment of Heart Failure
  26. Melflufen: A Journey from Discovery to Multi-Kilogram Production
  27. Discovery and Chemical Development of S 44563, a Dual Bcl-2/Bcl-xL Inhibitor
  28. Discovery and Chemical Development of Tesirine: An Antitumor Pyrrolobenzodiazepine Antibody-Drug Conjugate Drug-Linker
  29. Discovery and Chemical Development of Relebactam: A Potent β-Lactamase Inhibitor in Combination with PrimaxinŽ for the Treatment of Serious and Antibiotic-Resistant Bacterial Infections
  30. Discovery and Chemical Development of Grazoprevir: An HCV NS3/4a Protease Inhibitor for the Treatment of the Hepatitis C Virus Infection
  31. Discovery and Process Development of BIIB068: A Reversible Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Autoimmune Diseases
  32. Discovery and Commercial Development of Cholesteryl Transfer Protein Inhibitor Evacetrapib
  33. Editors’ Biographies
  34. Indexes
  35. Author Index
  36. Subject Index