Mechanistic Enzymology: Bridging Structure and Function

Justin M. Miller, Justin M. Miller, Chad Brambley, Jamie R. Wallen, David Ban, Jessica R. Krewall, Laura E. Minton, Douglas C. Goodwin, Tao Yu, Hong Guo, Chris Whittington, John Latham, Adam R. Offenbacher, Mitch H. Weiland, Justin M. Miller

• Publisher: American Chemical Society
• Year: 2020
• Print ISBN: 9780841298835
• eBook ISBN: 9780841298835

Table of contents

• Mechanistic Enzymology: Bridging Structure and Function
• ACS Symposium Series1357
• Foreword
• Introduction: Viewing Science through Multiple Lenses
• Enzyme Active Site Architecture: The Whole Is Greater Than the Sum of the Parts
• Integrative Structural Biology: Using X-ray Crystallography, Small-Angle X-ray Scattering, and Cryogenic Electron Microscopy to Determine Protein Structures
• Evolving Role of Conformational Dynamics in Understanding Fundamental Biomolecular Behavior
• KatG Structure and Mechanism: Using Protein-Based Oxidation to Confront the Threats of Reactive Oxygen
• Understanding Enzyme Catalysis Mechanism Using QM/MM Simulation Methods
• Tunneling through the Barriers: Resolving the Origins of the Activation of C-H Bonds Catalyzed by Enzymes
• Enzymatic Biodegradation by Exploring the Rational Protein Engineering of the Polyethylene Terephthalate Hydrolyzing Enzyme PETase from Ideonella sakaiensis 201-F6
• Editor Biography
• Indexes
• Author Index
• Subject Index
• Introduction: Viewing Science through Multiple Lenses
• Enzyme Active Site Architecture: The Whole Is Greater Than the Sum of the Parts
• Integrative Structural Biology: Using X-ray Crystallography, Small-Angle X-ray Scattering, and Cryogenic Electron Microscopy to Determine Protein Structures
• Evolving Role of Conformational Dynamics in Understanding Fundamental Biomolecular Behavior
• KatG Structure and Mechanism: Using Protein-Based Oxidation to Confront the Threats of Reactive Oxygen
• Understanding Enzyme Catalysis Mechanism Using QM/MM Simulation Methods
• Tunneling through the Barriers: Resolving the Origins of the Activation of C-H Bonds Catalyzed by Enzymes
• Enzymatic Biodegradation by Exploring the Rational Protein Engineering of the Polyethylene Terephthalate Hydrolyzing Enzyme PETase from Ideonella sakaiensis 201-F6
• Editor Biography
• Indexes
• Author Index
• Subject Index