Antidiabetic Plants for Drug Discovery

Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic Activity

Deepu Pandita, Anu Pandita, Chander Bhanu, Deepu Pandita, Anu Pandita, Chander Bhanu

• Publisher: Apple Academic Press
• Year: 2022
• eBook ISBN: 9781000575118
• Edition: 1
• Topic: Medicine
• Subtopic: Alternative & Complementary Medicine

This volume takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives.

Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as fl avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs

Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology. The specific plants discussed include Azadirachta indica (commonly known as neem, nimtree or Indian lilac), Gymnema sylvestre (commonly called gymnema, Australian cowplant, and Periploca of the woods), Syzygium cumini (commonly known as Malabar plum, Java plum, black plum, jamun or jambolana), Ceylon cinnamon (or true cinnamon, as opposed to cassia cinnamon), insulin plant (or Costus pictus), Trigonella foenum-graecum (better known as fenugreek), Mulberry, Nigella sativa L. (black caraway, also known as black cumin, nigella, kalojeera, kalonji or kalanji), Aegle marmelos (L.) (commonly known as bael (or bili or bhel), also Bengal quince, golden apple, Japanese bitter orange, stone apple or wood apple), Ficus benghalensis (the banyan, banyan fig and Indian banyan), and of course, garlic (Allium sativum).

Antidiabetic Plants for Drug Discovery: Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic Activity will serve as a valuable source of information for students, drug researchers, medical practitioners, diabetic patients, and many others in the effort to gain understand of how these plant drug molecules can help fight diabetes.

Table of contents

• Cover Page
• Half Title Page
• Title Page
• Copyright Page
• About the Editors
• Contents
• Contributors
• Abbreviations
• Preface
• 1 Azadirachta indica: Its Biological, Pharmacological, Antidiabetic Potential, and Omics Applications
• 2 Gymnema sylvestre (Asclepiadaceae): Multi-Potent Medicinal Plant with Potential for Antidiabetes and Obesity
• 3 Perspectives of Syzygium cumini (L.) Skeels, as a Potential Rational Herbal Medicine for Diabetes
• 4 Cinnamomum zeylanicum: Nature's Wonder Plant with Antidiabetic Prominence
• 5 Antidiabetic Potential of the Insulin Plant (Costus pictus)
• 6 Health Benefits of Trigonella foenum-graecum with Regard to Metabolomics of Antidiabetic Efficiency
• 7 Mulberry: From Root to Fruit with Antidiabetic Properties
• 8 The Antidiabetic Effect of Nigella sativa L. with Respect to Its Phytochemicals and the Mechanism of Action
• 9 Aegle marmelos (L.) as a Functional Food for Managing Diabetes Mellitus
• 10 Garlic (Allium sativum): A Potential Antidiabetic Agent
• 11 Antidiabetic Potential of Ficus benghalensis
• Index