In Nucleic Acids in Medicinal Chemistry and Chemical Biology: Drug Development and Clinical Applications, a team of distinguished researchers delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers.

The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field.

Readers will also find:

A thorough introduction to the basic terminology and knowledge of the field of nucleic acid medicinal chemistry
Comprehensive explorations of the methods used to determine the development of nucleic acid drugs
Practical discussions of new technologies, like CRISPR, nanotechnology-based delivery systems, synthetic biology, and DNA-encoded chemical libraries
In-depth examinations of the latest, cutting-edge developments in nucleic acid medicinal chemistry

Perfect for medicinal and nucleic acid chemists, Nucleic Acids in Medicinal Chemistry and Chemical Biology will also earn a place in the libraries of biochemists, chemical biologists, and pharmaceutical researchers.

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription.

No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn more here.

Perlego offers two plans: Essential and Complete

Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.

Both plans are available with monthly, semester, or annual billing cycles.

We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.

Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.

Yes! You can use the Perlego app on both iOS or Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.

Yes, you can access Nucleic Acids in Medicinal Chemistry and Chemical Biology by Lihe Zhang, Xinjing Tang, Zhen Xi, Jyoti Chattopadhyaya, Lihe Zhang,Xinjing Tang,Zhen Xi,Jyoti Chattopadhyaya in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Biological Sciences

Subtopic

Pharmacology

Index

Biological Sciences

COVER
TITLE PAGE
COPYRIGHT PAGE
CONTENTS
CONTRIBUTORS
FOREWORD
CHAPTER 1 DESIGN, SYNTHESIS, AND APPLICATIONS OF NUCLEOSIDE PHOSPHATE AND PHOSPHONATE PRODRUGS
CHAPTER 2 CYCLIC DINUCLEOTIDES: A NEW-GENERATION DRUG FOR IMMUNE THERAPY
CHAPTER 3 ENZYMATIC AND ENDOGENOUS SYNTHESIS OF NAD(P)-DERIVED CALCIUM-MOBILIZING MESSENGERS
CHAPTER 4 SELENIUM ATOM-MODIFIED NUCLEIC ACIDS FOR STRUCTURAL, FUNCTIONAL, AND DIAGNOSTIC STUDIES
CHAPTER 5 SEQUENCE-SPECIFIC CHROMOSOMAL DNA BINDERS: AN UNFULFILLED PROMISE?
CHAPTER 6 DNA SYNTHESIS AND SYNTHETIC GENOME
CHAPTER 7 METHODS FOR MAPPING OF NUCLEIC ACIDS EPIGENETIC MODIFICATIONS AND ITS CLINIC APPLICATIONS
CHAPTER 8 DNA-ENCODED CHEMICAL LIBRARIES USED FOR DRUG DISCOVERY
CHAPTER 9 NUCLEIC ACID–BASED NANOCARRIERS AS DRUG DELIVERY SYSTEM
CHAPTER 10 FLUORESCENCE HYBRIDIZATION IMAGING OF NEUROLOGICAL DISEASE MESSENGER RNAs
CHAPTER 11 PROGRESS OF OLIGONUCLEOTIDE THERAPEUTICS TARGET TO RNA: REVIEW ON MODIFICATION, CONJUGATION, AND DELIVERY:
CHAPTER 12 CRISPR/Cas9: A THERAPEUTIC SOLUTION BY MANIPULATING NUCLEIC ACIDS
CHAPTER 13 APTAMER PROPERTIES, FUNCTIONS, AND APPLICATIONS
CHAPTER 14 G-QUADRUPLEX AS A PLATFORM FOR NEW PERSPECTIVES IN NUCLEIC ACID TARGETING FOR THERAPEUTIC APPLICATIONS
INDEX
EULA

About this book

Frequently asked questions

Information

Table of contents