Liposomes in Gene Delivery
About this book
Many specialists are not familiar with both drug delivery and the molecular biology of DNA vectors. Liposomes in Gene Delivery covers both-molecular biologists will gain a basic knowledge of lipids, liposomes, and other gene delivery vehicles; lipid and drug delivery scientists will better understand DNA, molecular biology, and DNA manipulation. Topics include an introduction to nucleic acids, a theoretical description of DNA, recombinant technology, lipids and liposomes, stability and interaction properties of lipids and liposomes, complexation of lipids and liposomes with DNA plasmids, gene expression of genosomes in various models, structure-activity relationships, and transfection models. This is an excellent introductory text for graduate students, scientists, and researchers in molecular and cell biology, genetics, biochemistry, physical chemistry, colloid science, pharmacology, molecular science, and medicine.
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Information
Table of contents
- Cover
- Half Title
- Title Page
- Copyright Page
- DEDICATION
- PREFACE
- Table of Contents
- 1: Introduction
- 2: Gene Therapy
- 3: Nucleic Acids
- 4: Gene Expression
- 5: Gene Delivery
- 6: Liposomes
- 7: Genosomes (DNAâLipid Complexes)
- 8: Genosomes for Gene Delivery and Transfection
- 9: StructureâActivity Relationships
- 10: Mechanism of Transfection
- 11: Other Carrier Systems and Artificial Virus
- 12: Liposomes in the Delivery of Antisense Oligonucleotides
- 13: Perspectives and Conclusion
- Conclusion and Afterword
- References
- Appendix A: Some Fundamental Constants
- Appendix B: Periodic System of Elements
- Appendix C: A Short Tutorial on Different Units
- Appendix D: Geometric Parameters of Lipids and Nucleic Acids
- Appendix E: Abbreviations
- Appendix F: Glossary
- Index
