Handbook for Chemical Process Research and Development, Second Edition
eBook - ePub

Handbook for Chemical Process Research and Development, Second Edition

  1. 826 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Handbook for Chemical Process Research and Development, Second Edition

About this book

This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies.

Features:

  • This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner.
  • Promotes an industrial mindset concerning safety and commercial viability when developing methods.
  • The author discusses development strategies with case studies and experimental procedures.
  • Focuses on mechanism-guided process development which provides readers with practical strategies and approaches.
  • Addresses more common process issues such as safety, cost, robustness, and environmental impact.

This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.

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Yes, you can access Handbook for Chemical Process Research and Development, Second Edition by Wenyi Zhao in PDF and/or ePUB format, as well as other popular books in Medicine & Chemistry. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2023
Print ISBN
9781032759579
eBook ISBN
9781000859058
Edition
2
Subtopic
Chemistry

Table of contents

  1. Cover
  2. Half-Title
  3. Title
  4. Copyright
  5. Contents
  6. Preface
  7. Author Biography
  8. List of Abbreviations
  9. Chapter 1 Reaction Solvent Selection
  10. Chapter 2 Reagent Selection
  11. Chapter 3 Various Reagent Surrogates
  12. Chapter 4 Modes of Reagent Addition: Control of Impurity Formation
  13. Chapter 5 Process Optimization with Additives
  14. Chapter 6 Process Optimization of Catalytic Reactions
  15. Chapter 7 Process Optimization of Problematic Reactions
  16. Chapter 8 Hazards of Oxidation and Reduction Reactions
  17. Chapter 9 Other Hazardous Reactions
  18. Chapter 10 Hazardous Reagents
  19. Chapter 11 Grignard Reagent and Related Reactions
  20. Chapter 12 Challenging Reaction Intermediates
  21. Chapter 13 Protecting Groups
  22. Chapter 14 Telescope Approach
  23. Chapter 15 Design of New Synthetic Route
  24. Chapter 16 Stereochemistry
  25. Chapter 17 Various Quenching Strategies
  26. Chapter 18 Various Isolation and Purification Strategies
  27. Chapter 19 Methods for Residual Metal Removal
  28. Chapter 20 Methods for Impurity Removal
  29. Chapter 21 Pharmaceutical Salts
  30. Chapter 22 Solid Form
  31. Index