The Role of Nitric Oxide in Type 2 Diabetes
eBook - ePub

The Role of Nitric Oxide in Type 2 Diabetes

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

The Role of Nitric Oxide in Type 2 Diabetes

About this book

Type 2 diabetes (T2D) is a complex metabolic disorder characterized by impaired glucose metabolism and pancreatic ?-cell dysfunction. No effective treatments are available for T2D, although there have been many developments in the therapeutic arena. Nitric oxide (NO) is an endocrine agent with multiple and important biological roles in most mammalian tissues. NO has emerged as a central regulator of energy metabolism and body composition. NO bioavailability is decreased in T2D. Several of the pharmaceuticals used in T2D affect the NO system and perhaps even more so by the drugs we use to treat diabetic cardiovascular complications. Experimental works in animal models of T2D show promising results with interventions aimed to increase NO signaling. However, translation into human studies has so far been less successful, but more large-scale prolonged studies are clearly needed to understand its role.
This book is a collection of reviews that deal with the role of nitric oxide in type 2 diabetes, providing a unique overview of NO signaling, and pointing out key areas for more detailed research. The book includes contributions about the pathophysiology of T2D, a brief history of discovery and timeline of NO research, a comprehensive overview of impaired NO metabolism in T2D, precursors of NO (i.e., L-arginine, L-citrulline, nitrate, nitrites, and NO donors), NO and T2D from genetic points of view, NO and diabetic wound healing, NO and osteoporosis, NO and hyperuricemia, NO and Alzheimer's Disease, therapeutic applications of NO and NO donors in T2D. The compilation is of great value to anyone interested in the biochemistry of NO and its relationship to diabetes.

Trusted by 375,005 students

Access to over 1.5 million titles for a fair monthly price.

Study more efficiently using our study tools.

Information

Publisher
Bentham Science Publishers
Year
2003
Print ISBN
9789815079111
eBook ISBN
9789815079814
Topic
Medicine
Subtopic
Endocrinology & Metabolism

Table of contents

  1. Welcome
  2. Table of Content
  3. Title
  4. BENTHAM SCIENCE PUBLISHERS LTD.
  5. FOREWORD
  6. PREFACE
  7. List of Contributors
  8. Pathophysiology of Type 2 Diabetes: A General Overview of Glucose and Insulin Homeostasis
  9. Nitric Oxide: A Brief History of Discovery and Timeline of its Research
  10. Impaired Nitric Oxide Metabolism in Type 2 Diabetes: At a Glance
  11. Asymmetrical Dimethyl Arginine, Nitric Oxide, and Type 2 Diabetes
  12. Nitric Oxide-Related Oral Microbiota Dysbiosis in Type 2 Diabetes
  13. Nitric Oxide and Type 2 Diabetes: Lessons from Genetic Studies
  14. Role of Nitric Oxide in Diabetic Wound Healing
  15. Role of Nitric Oxide in Type 2 Diabetes-Induced Osteoporosis
  16. Hyperuricemia, Type 2 Diabetes and Insulin Resistance: Role of Nitric Oxide
  17. Therapeutic Management of Type 2 Diabetes: The Nitric Oxide Axis
  18. Brain Insulin Resistance, Nitric Oxide and Alzheimer’s Disease Pathology
  19. Arginine, Nitric Oxide, and Type 2 Diabetes
  20. Citrulline, Nitric Oxide, and Type 2 Diabetes
  21. Nitrate, Nitrite and Type 2 Diabetes
  22. Potential Applications of Nitric Oxide Donors in Type 2 Diabetes

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription
No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn how to download books offline
Perlego offers two plans: Essential and Complete
  • Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
  • Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.5M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Both plans are available with monthly, semester, or annual billing cycles.
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1.5 million books across 990+ topics, we’ve got you covered! Learn about our mission
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more about Read Aloud
Yes! You can use the Perlego app on both iOS and Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app
Yes, you can access The Role of Nitric Oxide in Type 2 Diabetes by Asghar Ghasemi,Khosrow Kashfi,Zahra Bahadoran, Asghar Ghasemi, Khosrow Kashfi, Zahra Bahadoran in PDF and/or ePUB format, as well as other popular books in Medicine & Endocrinology & Metabolism. We have over 1.5 million books available in our catalogue for you to explore.