Flow and Microreactor Technology in Medicinal Chemistry
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Flow and Microreactor Technology in Medicinal Chemistry
About this book
Learn to master a powerful technology to enable a faster drug discovery workflow
The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors—with integrated analysis of the resulting products—provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort.
In Flow and Microreactor Technology in Medicinal Chemistry, early adopters of this ground-breaking technology describe its current and potential uses in medicinal chemistry. Based on successful examples of the use of flow and microreactor synthesis for drug-like compounds, the book introduces current as well as emerging uses for automated synthesis in a drug discovery context.
Flow and Microreactor Technology in Medicinal Chemistry readers will also find:
- Numerous case studies that address the most common applications of this technology in the day-to-day work of medicinal chemists
- How to integrate flow synthesis with drug discovery
- How to perform enantioselective reactions under continuous flow conditions
Flow and Microreactor Technology in Medicinal Chemistry is a valuable practical reference for medicinal chemists, organic chemists, and natural products chemists, whether they are working in academia or in the pharmaceutical industry.
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Information
Table of contents
- Cover
- Table of Contents
- Title Page
- Copyright
- Series Editors Preface
- Volume Editor's Preface
- 1 Flow Chemistry at the Extremes: Turning Complex Reactions into Scalable Processes
- 2 Automated Flow Chemistry Platforms
- 3 Flow Chemistry Opportunities for Drug Discovery
- 4 Flow Chemistry in Medicinal Chemistry: Applications to Bcr‐Abl Kinase Inhibitors
- 5 Integrated Systems for Continuous Synthesis and Biological Screenings
- 6 Application of Continuous‐Flow Processing in Multistep API and Drug Syntheses
- 7 Continuous‐Flow Multistep Synthesis of Active Pharmaceutical Ingredients
- 8 Enantioselective (Bio)Catalysis in Continuous‐flow as Efficient Tool for the Synthesis of Advanced Intermediates and Active Pharmaceutical Ingredients
- 9 Innovative Process Development of Pharmaceutical Intermediates Under Continuous‐Flow System
- Index
- End User License Agreement