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Targeted Drug Delivery
About this book
Targeted Drug Delivery
Novel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugs
Targeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug carriers and devices, helping readers to stay up to date on the latest developments in the field.
The following key topics are addressed:
- Antibody conjugates, prodrugs, and suicide gene therapeutics
- Protac technology for selectively degrading target proteins
- Delivery of nucleic acid drugs
- Novel drug carriers, such as liposomes, vesicles, and nanoparticles
- Unmet medical needs for which there is a large market potential, such as viral infections and cancer
For chemists, pharmacologists, and professionals in the wider pharmaceutical industry, Targeted Drug Delivery is a comprehensive guide on how to solve the greatest challenge in treating many diseases: delivering a pharmaceutically active substance to the target tissue in the body.
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Information
Table of contents
- Cover
- Table of Contents
- Title Page
- Copyright
- A Personal Foreword
- Preface
- 1 Basics of Targeted Drug Delivery
- 2 Addressing Unmet Medical Needs Using Targeted Drug-Delivery Systems: Emphasis on Nanomedicine-Based Applications
- 3 Nanocarriers-Based Targeted Drug Delivery Systems: Small and Macromolecules
- 4 Liposomes as Targeted Drug-Delivery Systems
- 5 Antibody-Drug Conjugates: Development and Applications
- 6 Gene-Directed Enzyme-Prodrug Therapy (GDEPT) as a Suicide Gene Therapy Modality for Cancer Treatment
- 7 Targeted Prodrugs in Oral Drug Delivery
- 8 Exosomes for Drug Delivery Applications in Cancer and Cardiac Indications
- 9 Delivery of Nucleic Acids, Such as siRNA and mRNA, Using Complex Formulations
- 10 Application of PROTAC Technology in Drug Development
- 11 Metal Complexes as the Means or the End of Targeted Delivery for Unmet Needs
- 12 Formulation of Peptides for Targeted Delivery
- 13 Antibody-Based Targeted T-Cell Therapies
- 14 Devices for Active Targeted Delivery: A Way to Control the Rate and Extent of Drug Administration
- 15 Drug Delivery to the Brain: Targeting Technologies to Deliver Therapeutics to Brain Lesions
- Index
- End User License Agreement