Neurotherapeutics in the Era of Translational Medicine
eBook - ePub

Neurotherapeutics in the Era of Translational Medicine

  1. 518 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Neurotherapeutics in the Era of Translational Medicine

About this book

For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and researchers in the field of biotechnology, recounts the breathtaking advances that are revolutionizing treatment for disorders such as amyotrophic lateral sclerosis?, spinal muscular atrophy, multiple sclerosis, Parkinson's disease, myasthenia gravis, migraine, and glioblastoma. The "story behind the story" of these translational efforts is told, with authors depicting the ups and downs encountered on the path of their drug discovery and development effort. In parallel with this path, advances in identifying novel biomarkers and disease models are summarized, as are contemporary issues focusing on clinical trial design, bioethics, innovative funding strategies, and collaborations between government and academia in an effort to facilitate breakthrough treatments. The book is written by members of the biotech and pharmaceutical ecosystem for those who belong to it and aspire to become part of it.- Comprehensive review on the progress of translational research in neurotherapeutics for neurologic disorders- Discusses important issues in clinical trials such as design and ethical issues- Written for neuroscientists, neurologists and pharmacologists

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription.
No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn more here.
Perlego offers two plans: Essential and Complete
  • Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
  • Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Both plans are available with monthly, semester, or annual billing cycles.
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.
Yes! You can use the Perlego app on both iOS or Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Neurotherapeutics in the Era of Translational Medicine by Richard A. Smith,Brian K. Kaspar,Clive N. Svendsen in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Neuroscience. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Contributors
  6. Preface
  7. Prologue
  8. Chapter 1: Development of a molecular therapy for the SOD1 familial variant of ALS
  9. Chapter 2: Unraveling molecular biology of C9ORF72 repeat expansions in amyotrophic lateral sclerosis-frontotemporal dementia: Implications for therapy
  10. Chapter 3: Translating molecular therapies for spinal muscular atrophy
  11. Chapter 4: From uncovering the mechanism of transthyretin aggregation to the drug tafamidis for ameliorating neurodegeneration and cardiomyopathy
  12. Chapter 5: A novel treatment for Parkinson's disease and ALS: Combined cell and gene therapies
  13. Chapter 6: Parkinson's disease: Genetic-driven therapeutic approaches
  14. Chapter 7: Neural stem cell-mediated brain tumor therapy
  15. Chapter 8: Advances in migraine therapeutics: The role of calcitonin gene-related peptide
  16. Chapter 9: The impact of translational research on the development of therapeutic agents for multiple sclerosis
  17. Chapter 10: Advances in treating myasthenia gravis
  18. Chapter 11: The endocannabinoid system as a target for the treatment of neurological disorders
  19. Chapter 12: Identification of biomarkers for diagnosing and monitoring therapy in the treatment of neurologic disorders
  20. Chapter 13: 3D Alzheimer's disease in a dish: Implications for drug discovery
  21. Chapter 14: Improving clinical trial efficiency with machine learning models of disease progression
  22. Chapter 15: Positron emission tomography imaging agents for evaluating the pathologic features of Alzheimer's disease and drug development
  23. Chapter 16: Repurposing FDA-approved pharmaceuticals: The development of Nuedexta
  24. Chapter 17: Bioethics in the era of translational medicine
  25. Chapter 18: Government efforts to promote the development of neurotherapeutics for the treatment of neurological diseases
  26. Chapter 19: Innovative funding models for neurotherapeutics
  27. Index