YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer
eBook - ePub

YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer

A Critical Therapeutic Target

  1. 360 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer

A Critical Therapeutic Target

About this book

YY1 Is Pivotal in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes the current state-of-the-art of the transcription factor YY1 that is overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. This book emphasizes the biochemical, molecular and genetic underlying mechanisms by which YY1 regulates its pro-cancerous activities. In addition, it also describes the role of YY1 in the regulation of tumor cell resistance to conventional chemo and immunotherapies and the important role of inhibiting YY1 in cancer. This book is a valuable source for cancer researchers, oncologists and several members of medical and biomedical field who are interested in understanding further the role of YY1 in cancer. - Provides a thorough understanding of the underlying mechanisms by which YY1 regulates cancer cell phenotype and unique characteristics - Discusses the novel mechanisms of YY1 regulation of tumor cell resistance and means to overcome resistance - Encompasses new examples of newly developed non-toxic and selective inhibitors targeting YY1

Trusted by 375,005 students

Access to over 1.5 million titles for a fair monthly price.

Study more efficiently using our study tools.

Information

Publisher
Academic Press
Year
2020
Print ISBN
9780128219096
eBook ISBN
9780128226360
Topic
Biological Sciences
Subtopic
Biology
Index
Biological Sciences

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Copyright
  5. Aims and Scope
  6. About the Editor
  7. Preface
  8. Contributors
  9. List of Illustrations
  10. List of Tables
  11. Chapter 1 : The structure of Yin Yang 1 protein and its importance in the interaction with molecular partners
  12. Chapter 2 : YY1 and noncoding RNAs: A two-way relationship
  13. Chapter 3 : YY1 regulation of the cancer stem cell phenotype
  14. Chapter 4 : YY1 involvement in embryonic development and cancer
  15. Chapter 5 : Yin and Yang of YY1 regulation on tumor metabolic reprogramming
  16. Chapter 6 : YY1 and tumor metastasis regulation
  17. Chapter 7 : Molecular mechanisms of YY1 overexpression in human cancers and its prognostic significance
  18. Chapter 8 : YY1 is involved in the pathogenesis and malignant properties of human triple-negative breast cancer (TNBC)
  19. Chapter 9 : YY1 is a potential key player in the pathogenesis of malignant melanoma
  20. Chapter 10 : Participation of different miRNAs in the regulation of YY1: Their role in pathogenesis, chemoresistance, and therapeutic implication in hematologic malignancies
  21. Chapter 11 : Role, regulatory mechanism and clinical correlation of YY1 in HCC
  22. Chapter 12 : Targeting YY1 in cancer through histone acetylation
  23. Chapter 13 : The role of YY1 in drug resistant cancer: Involvement of the YY1/PTEN/PP2A/H2Ax/Rad51 axis
  24. Chapter 14 : Chemotherapy resistance and YY1
  25. Chapter 15 : Yin Yang 1 regulation of tumor cell resistance to chemotherapeutic drugs
  26. Chapter 16 : YY1-mediated regulation of type 2 diabetes via insulin
  27. Chapter 17 : YY1 expression and PD-1 regulation in CD8 T lymphocytes
  28. Chapter 18 : The role of YY1 in the pathogenesis of rheumatoid arthritis: A tale of cytokines, ncRNAs, and aberrant fibroblast-like synoviocytes (FLSs)
  29. Index
  30. A

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription
No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn how to download books offline
Perlego offers two plans: Essential and Complete
  • Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
  • Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.5M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Both plans are available with monthly, semester, or annual billing cycles.
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1.5 million books across 990+ topics, we’ve got you covered! Learn about our mission
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more about Read Aloud
Yes! You can use the Perlego app on both iOS and Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app
Yes, you can access YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer by Benjamin Bonavida in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over 1.5 million books available in our catalogue for you to explore.