Protein Biosynthesis Interference in Disease
eBook - ePub

Protein Biosynthesis Interference in Disease

  1. 296 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Protein Biosynthesis Interference in Disease

About this book

Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms of action, and influence over disease processes. This book examines the role of protein biosynthesis interference in Alzheimer's and other neurodegenerative conditions, cancer and inflammatory disorders, with specific attention paid to the biochemical dynamics of tryptamine, biogenic amines and aminoacyl-tRNA synthetases in these pathologies. Methods of regulating protein translation and interference mechanisms, including gene therapy, are presented, empowering biochemists, molecular biologists, disease researchers, and health professionals to understand the underlying factors of protein disease and improve patient outcomes. - Enables biochemists, molecular biologists and disease researchers to advance disease prevention, laboratory testing, and treatment pathways for protein biosynthesis interference related disorders - Examines the biochemical and molecular basis of protein biosynthesis interference in neurodegenerative disorders, cancer and inflammatory conditions, among other diseases - Analyzes tryptamine, biogenic amines, and aminoacyl-tRNA synthetases dynamics in protein translation and possible treatment pathways regulating protein biosynthesis

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Table of contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Preface
  6. Chapter 1. Introduction
  7. Chapter 2. Tryptamine in the diet, human microbiome, tRNA aminoacylation-protein biosynthesis, host-microbiota metabolic interactions
  8. Chapter 3. Dimethyltryptamine, methyltryptamine, hallucinations and metals
  9. Chapter 4. Psychoactive effects and toxicity of tryptamine, N-methyltryptamine (NMT), and N, N-dimethyltryptamine (DMT): quantification methods
  10. Chapter 5. Tryptamine in renal pathologies and in pregnancy
  11. Chapter 6. Tryptophanyl-tRNA synthetase (TrpRS) inhibition or TrpRS gene (WARS) mutations and deletion result to TrpRS deficiency and pathologies
  12. Chapter 7. Tryptamine in liver diseases and alcohol abuse
  13. Chapter 8. Tryptamine and tyramine in tobacco smoking
  14. Chapter 9. Tryptamine and other biogenic amines in human vaginal samples
  15. Chapter 10. Tryptamine and tryptophan in human fecal samples: diet alters tryptamine levels
  16. Chapter 11. Tryptamine in human noncataractous and cataractous eye lenses
  17. Chapter 12. Tryptamine toxicity in rats, adrenalectomy, toxicity prevention
  18. Chapter 13. Microorganisms: the natural producers of tryptamine in food
  19. Chapter 14. Human gut bacterial sequence associated with Alzheimerā€™s disease and biogenic amines
  20. Chapter 15. Diseases, factors and conditions associated with Alzheimerā€™s disease (AD) and dementia support a concept that AD is a widespread systemic disorder
  21. Chapter 16. Arterial hypertension is comorbidity in dementia and Alzheimerā€™s disease, tryptamine in metabolic syndrome
  22. Chapter 17. Whole blood viscosity: biogenic amines, dementia and Alzheimerā€™s disease
  23. Chapter 18. Tryptamine and aminoacyl-tRNAs in sleepā€“wake and circadian disruption
  24. Chapter 19. Senile plaques and/or neurofibrillary tangles in brain of non-demented individuals
  25. Chapter 20. Historical perspective and future research directions
  26. Chapter 21. Tryptamine content and effects in human and animals
  27. Chapter 22. Link of protein half-lives to neurodegeneration: tryptamine treatment effects
  28. Chapter 23. Alzheimerā€™s disease human gut microbiome associated sequence (ADAS): predictive disease modeling with ADAS: generating ADAS variants from human samples
  29. Chapter 24. Tryptamine and other biogenic amines (BA) as modifiable and degradable factors
  30. Chapter 25. Tryptamine and TrpRS in cancer and other conditions
  31. Chapter 26. Experimental procedures: tryptophanyl-tRNA synthetase (TrpRS) characterization
  32. Chapter 27. Tryptophanyl-tRNA synthetase (TrpRS) in phosphosignaling
  33. Chapter 28. Tryptophanyl-tRNA synthetase antigenic epitopes and mimotopes
  34. Chapter 29. Interactomes: tryptophanyl-tRNA synthetase forms and other aminoacyl-tRNA synthetases
  35. Chapter 30. Tryptophanyl-tRNA synthetase in cell and organism survival
  36. Chapter 31. Tryptophanyl-tRNA synthetase sharing epitopes
  37. Chapter 32. Tryptamine and tryptophanyl-tRNA synthetase in microvesicles, multivasicular bodies, and exosomes
  38. Chapter 33. Tryptophanyl-tRNA synthetase and tryptamine in protein kinase and cancer pathways
  39. Chapter 34. Global protein biosynthesis and aminoacyl-tRNA synthetase family
  40. References
  41. Index

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Yes, you can access Protein Biosynthesis Interference in Disease by Elena L. Paley in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biochemistry. We have over one million books available in our catalogue for you to explore.