Epigenetics and DNA Damage
eBook - ePub

Epigenetics and DNA Damage

  1. 336 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Epigenetics and DNA Damage

About this book

Although scientists recognize the role of epigenetic mechanisms in DNA damage response, the complex, mechanistic interplay between chromatin regulation and DNA repair is still poorly understood. Comprehending how these processes are connected in time and space and play out in developmental processes may reveal novel directions for new research and disease treatment. Epigenetics and DNA Damage, a new volume in the Translational Epigenetics series, offers a thorough grounding in the relationship between DNA Damage, epigenetic modifications, and chromatin regulation. Early chapters address the basic science of DNA damage and its association with various epigenetic mechanisms, including DNA methylation, post-translational histone modifications, histone variants, chromatin remodeling, miRNAs, and lncRNAs. This is followed by a close discussion of DNA damage and epigenetics in metabolism, aging, cellular differentiation, immune function, stem cell biology, and cancer, tying recent research to translational application in disease understanding. Later chapters examine possible epigenetic therapies combining DNA damage induction and epigenetic alteration, as well as instructive chapters on how to analyze DNA damage and epigenetic alterations in new research. - Offers a thorough foundation in epigenetics and DNA damage research, as well as informed discussion of evolving research trends, disease findings, and early therapeutics - Features chapter contributions from leading international contributors - Empowers scientists to apply protocols in DNA damage and epigenetic alteration analysis and experimatation in their own research

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Yes, you can access Epigenetics and DNA Damage by Miriam Galvonas Jasiulionis in PDF and/or ePUB format, as well as other popular books in Medicine & Genetics in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2022
Print ISBN
9780323910811
eBook ISBN
9780323910828
Topic
Medicine
Subtopic
Genetics in Medicine

Table of contents

  1. Epigenetics and DNA Damage
  2. Chapter 1 DNA damage and DNA methylation
  3. Chapter 2 DNA damage and histone modifications
  4. Chapter 3 DNA damage and histone variants
  5. Chapter 4 DNA damage and miRNAs
  6. Chapter 5 DNA damage and lncRNAs
  7. Chapter 6 DNA damage, sirtuins, and epigenetic marks
  8. Chapter 7 DNA damage, metabolism, and epigenetic regulation
  9. Chapter 8 DNA damage, epigenetics, and aging
  10. Chapter 9 DNA damage signaling, cell reprogramming, and differentiation
  11. Chapter 10 The interplay between DNA damage and epigenetics in cancer
  12. Chapter 11 Oncometabolites, epigenetic marks, and DNA repair
  13. Chapter 12 Cancer therapies inducing DNA damage
  14. Chapter 13 Epigenetic therapy and DNA damage response
  15. Chapter 14 Useful protocols to study DNA damage
  16. Chapter 15 Useful methods to study epigenetic marks: DNA methylation, histone modifications, chromatin structure, and noncoding RNAs
  17. Index