Peptide and Peptidomimetic Therapeutics
eBook - ePub

Peptide and Peptidomimetic Therapeutics

From Bench to Bedside

  1. 792 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Peptide and Peptidomimetic Therapeutics

From Bench to Bedside

About this book

Peptide and Peptidomimetic Therapeutics: From Bench to Beside offers applied, evidence-based instruction on developing and applying peptide therapeutics in disease treatment, driving drug discovery, and improving patient care. Here, researchers, clinicians and students will find tools to harness the full power of peptides and peptidomimetics and improve bioavailability, stability, efficiency and selectivity of new therapeutics and their application in treatment plans. More than 20 leaders in the field share their approaches for identifying and advancing peptide and peptidomimetic therapeutics. Topics examined run from "bench to bedside," beginning with fundamental peptide science, protein-protein interactions and peptide synthesis. Later chapters examine modes for peptide drug delivery, including cell penetration peptide and peptidomimetic delivery, as well as the targeting of specific disease types, peptide therapeutics as applied to infectious disease, cancer, metabolic disorders, neurodegenerative disorders, and skin disorders, and antiparasitic and immunosuppressive peptidomimetics. - Helps researchers and clinicians harness the full of power of peptides and peptidomimetics in their daily work and drug discovery - Features chapters running from "bench to bedside, providing a thorough grounding in fundamental peptide science, drug delivery methods, and targeting of specific disease types - Features chapter contributions from international leaders in peptide science and drug development

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Yes, you can access Peptide and Peptidomimetic Therapeutics by Nir Qvit,Samuel J.S. Rubin in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biochemistry. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Contents
  6. List of contributors
  7. Preface
  8. List of Illustrations
  9. List of Tables
  10. Chapter 1 : Therapeutic peptides: historical perspectives and current development trends
  11. Chapter 2 : Therapeutic peptidomimetics: targeting the undruggable space
  12. Chapter 3 : Tailoring peptides and peptidomimetics for targeting protein–protein interactions
  13. Chapter 4 : Advances in peptide synthesis
  14. Chapter 5 : Stapled peptidomimetic therapeutics
  15. Chapter 6 : Ring-closing metathesis/transannular cyclization to azabicyclo[X.Y.0]alkanone dipeptide turn mimics for biomedical applications
  16. Chapter 7 : The current state of backbone cyclic peptidomimetics and their application to drug discovery*
  17. Chapter 8 : Pharmacokinetics and pharmacodynamics of peptidomimetics
  18. Chapter 9 : Formulation of peptides and peptidomimetics
  19. Chapter 10 : Medical use of cell-penetrating peptides: how far have they come?
  20. Chapter 11 : Intracellular peptides as drug prototypes
  21. Chapter 12 : Applications of computational three-dimensional structure prediction for antimicrobial peptides
  22. Chapter 13 : Knottin peptidomimetics as therapeutics
  23. Chapter 14 : Venom peptides and peptidomimetics as therapeutics
  24. Chapter 15 : Therapeutic peptides targeting protein kinase: progress, challenges, and future directions, featuring cancer and cardiovascular disease
  25. Chapter 16 : Therapeutic peptidomimetics for infectious diseases
  26. Chapter 17 : Antiparasitic therapeutic peptidomimetics
  27. Chapter 18 : Peptides and antibiotic resistance
  28. Chapter 19 : Antimicrobial peptides and the skin and gut microbiomes
  29. Chapter 20 : Peptide and peptidomimetic-based vaccines
  30. Chapter 21 : Therapeutic peptidomimetics for cancer treatment
  31. Chapter 22 : Immunomodulatory peptidomimetics for multiple sclerosis therapy—the story of glatiramer acetate (Copaxone)
  32. Chapter 23 : Therapeutic peptidomimetics in metabolic diseases
  33. Chapter 24 : Peptide therapeutics in anesthesiology
  34. Chapter 25 : Cardiovascular-derived therapeutic peptidomimetics in cardiovascular disease
  35. Chapter 26 : Noncardiovascular-derived therapeutic peptidomimetics in cardiovascular disease
  36. Chapter 27 : Clinical and preclinical data on therapeutic peptides
  37. Chapter 28 : Therapeutic peptides: market and manufacturing
  38. Chapter 29 : Future perspectives on peptide therapeutics
  39. Index
  40. A