eBook - ePub
Addition, Elimination and Substitution: Markovnikov, Hofmann, Zaitsev and Walden
Discovery and Development
- 280 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Addition, Elimination and Substitution: Markovnikov, Hofmann, Zaitsev and Walden
Discovery and Development
About this book
Addition, Elimination and Substitution: Markovnikov, Hofmann, Zaitsev and Walden: Discovery and Development discusses foundational reactions in organic chemistry and their major protagonists, contributions to synthesis, and history. Hofmann, Zaitsev, and Markovnikov are introduced, along with their major discoveries and contributions to organic chemistry. The history of controversies around Markovnikov's Rule are addressed. The book introduces Walden's original demonstration of configuration inversion, then discusses bimolecular elimination reactions, regioselective addition reactions, regiospecific alkene synthesis, and the development of modern reactions with configuration inversion. With its unique perspective, focus, and comprehensive coverage, this book belongs on the shelf of every organic chemist.
- Introduces Markovnikov, Zaitsev, Hofmann, and Walden as actual persons, rather than just an abstract term used as a form of short-hand to describe the rules
- Discusses, in depth, the discovery and usage of these reactions and rules, from their discovery to their most recent applications
- Includes biographical materials about chemists responsible for major changes in application of the rules
- Traces the history of the applications of these reactions, e.g., anti-Markovnikov additions in catalytic organic synthesis, and reactions such as the Mitsunobu reaction improving the original SN2 displacement
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Addition, Elimination and Substitution: Markovnikov, Hofmann, Zaitsev and Walden by David E. Lewis in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Biochemistry. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Cover
- Front Matter
- Table of Contents
- Copyright
- List of Illustrations
- List of Tables
- Chapter one : Introduction: Organic Chemistry in the Nineteenth Century
- Chapter TWO : Vladimir Vasil'evich Markovnikov and his rule for addition
- Chapter Three : Markovnikov's rule: history and development
- Chapter Four : Aleksandr Mikhailovich Zaitsev and his empirical rule for elimination
- Chapter Five : August Wilhelm von Hofmann and Hofmann's rule for elimination
- Chapter Six : Paul Walden and the Walden inversion
- Chapter Seven : Mechanistic studies
- Chapter Eight : Development of highly regioselective addition reactions of alkenes and alkynes
- Chapter Nine : Development of highly regiospecific alkene syntheses: elimination and its substitutes
- Chapter Ten : Inversion of configuration in modern synthesis
- Index
- A