Discoveries in Pharmacology - Volume 1 - Nervous System and Hormones

Clive Page, Jacques Bruinvels, Michael J. Parnham

• Publisher: Academic Press
• Year: 2022
• ISBN:
  9780323855204
• Edition: 2
• Topic: Medicine
• Subtopic: Pharmacology

Discoveries in Pharmacology: Volume 1: Nervous system and hormones (2nd Ed.) presents selected articles from the historic Discoveries in Pharmacology series enhanced with commentary from contemporary scholars about the reception and importance of the chapter along with an updated bibliography on the subject with contributions from a Nobel Prize winner and other pioneers in Pharmacology. The Discoveries in Pharmacology series brought acknowledged experts in their fields together to provide first-hand accounts of important pharmacological discoveries discussing the scientific background and stories behind these pivotal moments. They allow a true understanding of the means by which pharmacological discoveries are made. This volume brings forth discussions on key discoveries in psycho- and neuro-pharmacology, haemodynamics, and hormones including chapters on antipsychotic agents by Nobel winner Anders Carlsson, Willy Haefely on benzodiazepine, and butyrophenone-type neuroleptics by P. A. J. Janssen and J. P. Tollenaere. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area will find this series a useful teaching tool and launch to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. It will also be of interest to those who are interested in the history of medicine.

• Contains primary-source documents currently unavailable
• Presents the science behind major pharmacological breakthroughs by those who discovered them
• Includes commentary that contextualizes the importance of discoveries and related readings

Table of contents

• Cover Image
• Title Page
• Copyright
• Table of Contents
• Contributors
• Preface
• Chapter 1A Commentary on Chemical transmission of nerve impulses by Zénon M. Bacq
• Chapter 1B Chemical transmission of nerve impulses
• Chapter 2A Commentary on Discovery of the clinical use of neuroleptics by Pierre Deniker
• Chapter 2B The suppression of psychotic behaviour -- Discovery of the clinical use of neuroleptics
• Chapter 3A Commentary on The discovery of the butyrophenone-type neuroleptics by P.A.J. Janssen and J.P. Tollenaere
• Chapter 3B The suppression of psychotic behaviour -- The discovery of the butyrophenone-type neuroleptics
• Chapter 4A Commentary on: Antipsychotic agents: elucidation of their mode of action by Arvid Carlsson
• Chapter 4B The suppression of psychotic behaviour -- Antipsychotic agents: elucidation of their mode of action
• Chapter 5A Commentary on Clinical discoveries with antidepressant drugs by Heinz E. Lehmann and Nathan S. Kline
• Chapter 5B Antidepressants: Clinical discoveries with antidepressant drugs
• Chapter 6A Commentary on Monoamine oxidase and its inhibitors in relation to antidepressive activity by E. Albert Zeller
• Chapter 6B Antidepressants: Monoamine oxidase and its inhibitors in relation to antidepressive activity
• Chapter 7A Commentary on The discovery of tricyclic antidepressants and their mode of action by F. Sulser and R. Mishra
• Chapter 7B The discovery of tricyclic antidepressants and their mode of action
• Chapter 8A Parkinson's treatment in perspective. Commentary on Levodopa and dopamine agonists in the treatment of Parkinson's disease by Theodore L. Sourkes and Serge Gauthier
• Chapter 8B Levodopa and dopamine agonists in the treatment of Parkinson's disease
• Chapter 9A Commentary on Alleviation of anxiety: the benzodiazepine saga by Willy Haefely
• Chapter 9B Alleviation of anxiety — the benzodiazepine saga
• Chapter 10A The development of antiseizure medications. Commentary on The development of antiepileptic drugs by J.W.A. Meijer, H. Meinardi, and C.D. Binnie
• Chapter 10B The development of antiepileptic drugs
• Chapter 11A Commentary on Analgesia up to the Twentieth Century by Peter Holzer and Fred Lembeck
• Chapter 11B Analgesia up to the twentieth century
• Index