NK Cells in Cancer Immunotherapy: Successes and Challenges
eBook - ePub

NK Cells in Cancer Immunotherapy: Successes and Challenges

  1. 494 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

NK Cells in Cancer Immunotherapy: Successes and Challenges

About this book

NK Cells in Cancer Immunotherapy: Successes and Challenges explains the latest immunotherapeutic strategies, focusing on NK cells to allow the best and precise combination treatments to cancer patients. The book provides existing background knowledge in the field of immunotherapy and discusses future areas of research required to carry out cutting-edge, validated therapies. Chapters cover advances in immunotherapeutic strategies, in particular, the use of NK cells with and without T-cell therapy in the treatment of cancer. The book is a valuable resource for cancer researchers, oncologists, graduate students and those interested in learning more about novel strategies to treat cancer patients. Immunotherapy is fast becoming the method of choice for cancer therapy. Although remarkable advances have been made in the field of immunotherapy, there are significant challenges and difficulties ahead since many of the current immunotherapeutic strategies do not provide long-lasting treatment strategies, and therefore are not very effective. - Covers CAR/T and CAR/NK and adoptive NK cell therapy with and without T cell therapies - Discusses basic biology of NK cells and mouse models of human cancers and the role of NK cells in metastatic cancer and in cancer stem cells - Encompasses information on combination therapies using check point inhibition, adoptive transfer of cytotoxic effector cells, chemotherapeutic drugs and activating and inhibitory antibodies

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Yes, you can access NK Cells in Cancer Immunotherapy: Successes and Challenges by Anahid Jewett,Yuman Fong in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2022
Print ISBN
9780128226209
eBook ISBN
9780128226261
Topic
Biological Sciences
Subtopic
Biology
Index
Biological Sciences

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Copyright
  5. Cover Image Insert
  6. Aims and Scope of Series ā€œBreaking Tolerance to Anti-Cancer Cell-Mediated Immunotherapyā€
  7. About the Series Editor
  8. Aims and Scope of Volume
  9. About the Volume Editors
  10. Prefaceā€”Cellular immunotherapies: Evolution from laboratory studies to effective human therapies
  11. Contributors
  12. List of Illustrations
  13. List of Tables
  14. Chapter 1 : Multifaceted nature of natural killer cells: Potential mode of interaction and shaping of stem cells
  15. Chapter 2 : Reversing the NK inhibitory tumor microenvironment by targeting suppressive immune effectors
  16. Chapter 3 : Natural killer cells as immunotherapeutic effectors for solid tumors
  17. Chapter 4 : Targeting NKG2D/NKG2D ligand axis for cancer immunotherapy
  18. Chapter 5 : Chimeric antigen receptor-modified cells for the treatment of solid tumors: First steps in a thousand-mile march
  19. Chapter 6 : Tumor-infiltrating lymphocyte (TIL) therapy
  20. Chapter 7 : Biology and status of chimeric antigen receptor-engineered T cell therapy
  21. Chapter 8 : Optimization of production for cell therapies
  22. Chapter 9 : Lymphodepletion and cellular immunotherapy
  23. Chapter 10 : Imaging the immune cell in immunotherapy
  24. Chapter 11 : Radiologic assessment of tumor response to immunotherapy and its complications
  25. Chapter 12 : Novel cell delivery systems: Intracranial and intrathecal
  26. Chapter 13 : Diagnostic methods to assess the numbers, phenotype, and function of primary and engineered NK cells: Methods to predict prognosis and treatment outcome
  27. Chapter 14 : Combination of NK cell immunotherapy with chemotherapy and radiation enhances NK cell therapy and provides improved prognosis in cancer patients and in humanized BLT mouse model system
  28. Chapter 15 : Combining oncolytic viruses with immune cell therapy as treatments for cancer: OV, CAR T-cell, and NK combinations
  29. Chapter 16 : Natural killer cells in the treatment of glioblastoma: Diverse antitumor functions and potential clinical applications
  30. Chapter 17 : Immunotherapy using CAR T: What we have learned from trials and where we are heading
  31. Chapter 18 : NKT cell: Success and promises in transplantation and immunotherapy
  32. Chapter 19 : Tumor-infiltrating lymphocytes: Prognostic considerations and current trials as adoptive cell therapy
  33. Chapter 20 : Molecular remission using personalized low-dose immunotherapy with minimal toxicities for poor prognosis hematological and solid tumor cancers
  34. Index
  35. A