Contemporary Management of Metastatic Colorectal Cancer

A Precision Medicine Approach

Aslam Ejaz, Timothy M. Pawlik

• Publisher: Academic Press
• Year: 2022
• Print ISBN:
  9780323917063
• eBook ISBN:
  9780323985680
• Topic: Business
• Subtopic: Business Intelligence
• Index: Business

Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach summarizes current knowledge and provides evidenced-based practice recommendations on how to treat patients with metastatic colorectal cancer. The book presents topics such as pre-operating imaging, the use of molecular markers in treatment decisions, neoadjuvant therapy, synchronous colorectal liver metastasis, and minimally invasive approaches. In addition, it discusses immunotherapy, targeted therapies and survivorship. This is a valuable resource for practitioners, cancer researchers, oncologists, graduate students and members of biomedical research who need to understand more about novel treatments for colorectal cancer metastasis. - Summarizes contemporary data in the workup and treatment of patients with metastatic colorectal cancer - Discusses novel patient-centric personalized approaches surrounding the management of such cancer types - Presents evidenced-based recommendations for precision care among patients with metastatic colorectal cancer

Table of contents

• Cover Image
• Title Page
• Copyright
• Dedication
• Table of Contents
• Contributors
• Preface
• Chapter 1 Epidemiology and risk factors for metastatic colorectal disease
• Chapter 2 The tumor microenvironment of colorectal cancer liver metastases: Molecular mediators and future therapeutic targets
• Chapter 3 Pre-operative imaging, response evaluation, and surgical planning – CT, PET, radiomics, and FLR measurement
• Chapter 4 Use of molecular markers and other personalized factors in treatment decisions for metastatic colorectal cancer
• Chapter 5 Role of Neoadjuvant therapy in the treatment of patients with colorectal liver metastases
• Chapter 6 Management of the disappeared colorectal liver metastasis
• Chapter 7 Approach to small liver remnant – strategies to increase resectability
• Chapter 8 Two-stage versus ALPPS for large intrahepatic burden of colorectal liver metastasis
• Chapter 9 Synchronous colorectal liver metastasis – simultaneous vs. staged approach
• Chapter 10 Minimally invasive approaches to colorectal liver metastases
• Chapter 11 Hepatic resection of colorectal liver metastasis in the presence of extrahepatic disease
• Chapter 12 Locoregional approaches to colorectal liver metastasis – ablation
• Chapter 13 Locoregional approaches to colorectal liver metastasis – intra-arterial
• Chapter 14 Locoregional Approaches to Colorectal Liver Metastasis – Radiation Options
• Chapter 15 Immunotherapy and targeted therapies for colorectal liver metastasis
• Chapter 16 Adjuvant therapy following resection of colorectal liver metastases
• Chapter 17 Long-term prognosis and surveillance of patients with resected colorectal liver metastasis
• Chapter 18 Management of secondary recurrence of intra-hepatic colorectal liver metastasis following initial hepatic resection
• Chapter 19 Colorectal liver metastasis: survivorship
• Index