
- 1,556 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Reproductive and Developmental Toxicology
About this book
**Selected for Doody's Core Titles® 2024 in Toxicology**Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife
With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies.
- Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development
- Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis
- Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more
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Yes, you can access Reproductive and Developmental Toxicology by Ramesh C Gupta,Ramesh C. Gupta in PDF and/or ePUB format, as well as other popular books in Medicine & Gynecology, Obstetrics & Midwifery. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Cover
- Front Matter
- Table of Contents
- Copyright
- Dedication
- Contributors
- Introduction
- List of Illustrations
- List of Tables
- Chapter 1 : Reproductive anatomy and physiology
- Chapter 2 : Pharmacokinetics in pregnancy
- Chapter 3 : Physiologically based pharmacokinetic models in reproductive and developmental toxicology
- Chapter 4 : Adverse Outcome Pathways in reproductive and developmental toxicology
- Chapter 5 : Juvenile toxicology testing
- Chapter 6 : Relevance of animal testing and sensitivity of end points in reproductive and developmental toxicity
- Chapter 7 : Alternative methods to animal experimentation for testing developmental toxicity
- Chapter 8 : Use of computational toxicology tools to predict in vivo endpoints
- Chapter 9 : Guidelines for reproductive and developmental toxicity testing and risk assessment of chemicals
- Chapter 10 : Reproductive toxicity: in vivo testing guidelines from OECD
- Chapter 11 : In vitro biomarkers of developmental neurotoxicity
- Chapter 12 : Reproductive and developmental safety evaluation of new pharmaceutical compounds
- Chapter 13 : Using zebrafish to assess developmental neurotoxicity
- Chapter 14 : Caenorhabditis elegans as a model to assess reproductive and developmental toxicity
- Chapter 15 : Postmarket surveillance and regulatory considerations in reproductive and developmental toxicology: a Food and Drug Administration perspective
- Chapter 16 : Developmental toxicity of engineered nanomaterials
- Chapter 17 : Effects of ionizing radiation on reproduction and development
- Chapter 18 : Reproductive and developmental toxicity of solvents and gases
- Chapter 19 : Developmental neurotoxicity of drugs of abuse
- Chapter 20 : Effects of alcohol on embryo/fetal development
- Chapter 21 : Cigarette and E-cigarettes smoking and reproductive and developmental toxicity
- Chapter 22 : Thalidomide
- Chapter 23 : Retinoids
- Chapter 24 : Safety of cannabis- and hemp-derived constituents in reproduction and development
- Chapter 25 : Caffeine
- Chapter 26 : Melamine and cyanuric acid
- Chapter 27 : Ionophores
- Chapter 28 : Boron
- Chapter 29 : Arsenic, cadmium, and lead
- Chapter 30 : Mercury
- Chapter 31 : Manganese
- Chapter 32 : Selenium
- Chapter 33 : Organophosphates and carbamates
- Chapter 34 : Chlorinated hydrocarbons and pyrethrins/pyrethroids
- Chapter 35 : Herbicides and fungicides
- Chapter 36 : Brominated flame retardants
- Chapter 37 : Polychlorinated biphenyls, polybrominated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans
- Chapter 38 : Reproductive toxicity of polycyclic aromatic hydrocarbons
- Chapter 39 : Bisphenol A—toxicity and risk assessment update with academic and regulatory perspectives and physiologically based pharmacokinetic modeling
- Chapter 40 : Ethylene glycol
- Chapter 41 : Perfluorooctane sulfonate and perfluorooctanoic acid
- Chapter 42 : Traffic-related air pollution and the developing brain
- Chapter 43 : Environmental pollutants and embryonic implantation and embryonic development
- Chapter 44 : Personal care products and cosmetics
- Chapter 45 : UV screening chemicals
- Chapter 46 : Toxic plants
- Chapter 47 : Fumonisins
- Chapter 48 : Aflatoxins, ochratoxins, and citrinin
- Chapter 49 : Trichothecenes and zearalenone
- Chapter 50 : Drugs and chemical contaminants in human breast milk
- Chapter 51 : Stem cells in developmental toxicity testing
- Chapter 52 : Embryonic and fetal toxic lesions and stem cell therapy
- Chapter 53 : Epigenetics in reproduction and development
- Chapter 54 : Mitochondrial dysfunction in reproductive and developmental toxicity
- Chapter 55 : Cell signaling mechanisms in developmental neurotoxicity
- Chapter 56 : Neuroinflammation and oxidative injury in developmental neurotoxicity
- Chapter 57 : Effects of stress on reproductive function and fetal development
- Chapter 58 : Endocrine disruption
- Chapter 59 : Role of endocrine disruptors in male infertility and impact of COVID-19 on male reproduction
- Chapter 60 : Toxicology of reproduction process and problems of male infertility
- Chapter 61 : Environmental pollutants and neural tube defects
- Chapter 62 : Teratogenicity
- Chapter 63 : Micro-CT and volumetric imaging in developmental toxicology
- Chapter 64 : Toxicologic pathology of the reproductive system
- Chapter 65 : The placental role in developmental programming
- Chapter 66 : Strategies for investigating hemochorial placentation
- Chapter 67 : The significance of ABC transporters in human placenta for the exposure of fetus to xenobiotics
- Chapter 68 : Placental toxicity
- Chapter 69 : Placental pathology
- Chapter 70 : Endocrine disruption in wildlife species
- Chapter 71 : Teratogenesis in livestock
- Chapter 72 : Reproductive and developmental toxicity in avian species
- Index
- A