Oral Delivery of Therapeutic Peptides and Proteins
eBook - ePub

Oral Delivery of Therapeutic Peptides and Proteins

  1. 316 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Oral Delivery of Therapeutic Peptides and Proteins

About this book

Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource. - Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems - Examines developing technologies to improve future oral bioavailability - Includes the in vitro and preclinical techniques needed for development

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Yes, you can access Oral Delivery of Therapeutic Peptides and Proteins by Puneet Tyagi,Anand Subramony in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Pharmaceutical, Biotechnology & Healthcare Industry. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Oral Delivery of Therapeutic Peptides and Proteins
  2. Chapter one Landscape for oral delivery of peptides
  3. Chapter two Design and synthesis of chemically modified peptides and proteins —critical considerations for oral delivery
  4. Chapter Three A biopharmaceutics perspective on oral peptide developability and drug delivery
  5. Chapter four Nanoparticle-assisted oral delivery of small and large peptides
  6. Chapter five Novel formulation approaches for gastrointestinal targeting: characterization and animal model considerations
  7. Chapter six CMC Considerations for conventional oral peptide formulations. Scale up and validation
  8. Chapter seven Clinical translation of oral peptide delivery technologies
  9. Chapter eight Regulatory aspects of oral peptide delivery
  10. Index