Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes

Tharmalingam Punniyamurthy, Anil Kumar, Tharmalingam Punniyamurthy, Anil Kumar

• Publisher: Wiley
• Year: 2023
• Print ISBN: 9781119774136
• eBook ISBN: 9781119774150
• Edition: 1
• Topic: Physical Sciences
• Subtopic: Industrial & Technical Chemistry

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles

A comprehensive guide to recent advances in this field

Constituting the majority of all known compounds, heterocycles are structures that incorporate one or more heteroatoms within their core, thus exhibiting properties that are quite different from their all-carbon analogs. They are fundamental to all fields of chemistry and, therefore, their synthesis and modification has attracted a great deal of attention in the recent years. In this vein, transition-metal-catalyzed C-H bond functionalization forms a crucial tool for generating and analyzing heterocyclic compounds.

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume Set, showcases diverse C-H functionalization methodologies and their incorporation into the latest research. The chapters serve as an essential tool depicting detailed site-selective functionalization of heterocyclic cores, along with a comprehensive discussion on their mechanistic approaches.

Readers of Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set will also find:

• A detailed introduction to C-H activation along with the mechanistic aspects of transition-metal-catalyzed C-H bond activation reactions
• Easy-to-use structures with each chapter dedicated to a type of heterocycle and its specific functionalization methodologies
• A leading team of international authors in C-H bond functionalization

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set is a valuable guide for students and researchers in organic synthesis and process development, in both academic and industrial contexts.

Table of contents

• Transition-Metal-Catalyzed C-H Functionalization of Heterocycles Volume 1
• Cover
• Title page
• Copyright
• Brief Contents
• Table of Contents
• List of Contributors
• Preface
• 1 Historical Perspective and Mechanistic Aspects of C–H Bond Functionalization
• 2 Recent Advances in C–H Functionalization of Five–Membered Heterocycles with Single Heteroatoms
• 3 Functionalization of Five-membered Heterocycles with Two Heteroatoms
• 4 Transition Metal-Catalyzed C–H Functionalization of Indole Benzenoid Ring
• 5 Transition Metal-Catalyzed C2 and C3 Functionalization of Indoles
• 6 C(sp2)–H Functionalization of Indolines at the C7-Position
• 7 Transition Metal-Catalyzed C–H Functionalization of Benzofused Azoles with Two or More Heteroatoms
• 9 Transition Metal-catalyzed C-H Bond Functionalization of Diazines and Their Benzo Derivatives
• 10 Functionalization of Chromenes and Their Derivatives
• 11 Transition Metal-Catalyzed C–H Functionalization of Imidazo-fused Heterocycles
• 12 Dehydrogenative Annulation of Heterocycles: Synthesis of Fused Heterocycles
• 13 C–H Functionalization of Saturated Heterocycles Beyond the C2 Position
• 14 Asymmetric Functionalization of C–H Bonds in Heterocycles
• 15 Transition Metal-Catalyzed C–H Functionalization of Nucleoside Bases
• 16 C–H Activation for the Synthesis of C1-(hetero)aryl Glycosides
• 17 Late-stage C–H Functionalization: Synthesis of Natural Products and Pharmaceuticals
• 18 Late-stage Functionalization of Pharmaceuticals, Agrochemicals, and Natural Products
• Index
• End User License Agreement