Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry

Industrial and Environmental Applications

Haroun N. Shah, Saheer E. Gharbia, Ajit J. Shah, Erika Y. Tranfield, K. Clive Thompson

• Publisher: Wiley
• Year: 2023
• Print ISBN: 9781119814054
• eBook ISBN: 9781119814078
• Edition: 1
• Topic: Physical Sciences
• Subtopic: Spectroscopy & Spectrum Analysis

Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry

Detailed resource presenting the capabilities of MALDI mass spectrometry (MS) to industrially and environmentally significant areas in the biosciences

Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry fulfills a need to bring the key analytical technique of MALDI mass spectrometric analysis into routine practice by specialists and non-specialists, and technicians. It informs and educates established researchers on the development of techniques as applied to industrially significant areas within the biosciences. Throughout the text, the reader is presented with recognized and emerging techniques of this powerful and continually advancing field of analytical science to key areas of importance.

While many scientific papers are reporting new applications of MS-based analysis in specific foci, this book is unique in that it draws together an incredibly diverse range of applications that are pushing the boundaries of MS across the broad field of biosciences.

Contributed to by recognized experts in the field of MALDI MS who have been key players in promoting the advancement and dissemination of authoritative information in this field, Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry covers sample topics such as:

• Oil microbiology, marine and freshwater ecosystems, agricultural and food microbiology, and industrial waste microbiology
• Bioremediation and landfill sites microbiology, microbiology of inhospitable sites (e.g. Arctic and Antarctic, and alkaline and acidic sites, and hot temperatures)
• Veterinary, poultry and animals, viral applications of MS, and antibiotic resistance using tandem MS methods
• Recent developments which are set to transform the use of MS from its success in clinical microbiology to a wide range of commercial and environmental uses

Bridging the gap between measurement and key applications, this text is an ideal resource for industrial and environmental analytical scientists, including technologists in the food industry, pharmaceuticals, and agriculture, as well as biomedical scientists, researchers, clinicians and academics and scientists in bio-resource centers.

Table of contents

• Cover
• Table of Contents
• Title Page
• Copyright Page
• Dedication Page
• List of Contributors
• Preface
• 1 Progress in the Microbiological Applications of Mass Spectrometry: from Electron Impact to Soft Ionization Techniques, MALDI‐TOF MS and Beyond
• 2 Machine Learning in Analysis of Complex Flora Using Mass Spectrometry
• 3 Top‐down Identification of Shiga Toxin (and Other Virulence Factors and Biomarkers) from Pathogenic E. coli using MALDI‐TOF/TOF Tandem Mass Spectrometry
• 4 Liquid Atmospheric Pressure (LAP) – MALDI MS(/MS) Biomolecular Profiling for Large‐scale Detection of Animal Disease and Food Adulteration and Bacterial Identification
• 5 Development of a MALDI‐TOF Mass Spectrometry Test for Viruses
• 6 A MALDI‐TOF MS Proteotyping Approach for Environmental, Agricultural and Food Microbiology
• 7 Diversity, Transmission and Selective Pressure on the Proteome of Pseudomonas aeruginosa
• 8 Characterization of Biodegradable Polymers by MALDI‐TOF MS
• 9 Phytoconstituents and Antimicrobiological Activity
• 10 Application of MALDI‐TOF MS in Bioremediation and Environmental Research
• 11 From Genomics to MALDI‐TOF MS: Diagnostic Identification and Typing of Bacteria in Veterinary Clinical Laboratories
• 12MALDI‐TOF MS Analysis for Identification of Veterinary Pathogens from Companion Animals and Livestock Species
• 13MALDI‐TOF MS: from Microbiology to Drug Discovery
• 14 Rapid Pathogen Identification in a Routine Food Laboratory Using High‐throughput MALDI‐TOF Mass Spectrometry
• 15 Detection of Lipids in the MALDI Negative Ion Mode for Diagnostics, Food Quality Control, and Antimicrobial Resistance
• 16 Use of MALDI‐TOF MS in Water Testing Laboratories
• 17 A New MALDI‐TOF Database Based on MS Profiles of Isolates in Icelandic Seawaters for Rapid Identification of Marine Strains
• 18MALDI‐TOF MS Implementation Strategy for a Pharma Company Based upon a Network Microbial Identification Perspective
• 19MALDI‐TOF MS – Microbial Identification as Part of a Contamination Control Strategy for Regulated Industries
• 20 Identification of Mold Species and Species Complex from the Food Environment Using MALDI‐TOF MS
• Index
• End User License Agreement