Organozinc Derivatives and Transition Metal Catalysts

Formation of C-C Bonds by Cross-coupling

Janine Cossy

• Publisher: De Gruyter
• Year: 2023
• eBook ISBN: 9783110728941
• Edition: 1
• Topic: Physical Sciences
• Subtopic: Analytic Chemistry

Organozinc reagents are less reactive than Grignard reagents but they are much more chemoselective. Since the Negishi cross-coupling reaction developed by Ei-ichi Negishi, who was awarded the Nobel Price in chemistry in 2010, a number of cross-coupling reactions involving organozinc derivatives and transition metal catalysts (Pd, Ni, Fe, Co, Cu, …) has been tuned up to form C-C bonds. This book on "Organozinc derivatives and transition metal catalysts" has been written by experts in the field and is a complement to the book entitled "Grignard reagents and transition metal catalysts" (a De Gruyter book, edited by J. Cossy).

Grignard reagents or organozinc reagents, that is the question? From a given substrate, what is the best organometallic reagent and the best transition metal to form a C-C bond by using a cross-coupling reaction? The solution might be found in these two books.

Table of contents

• Title Page
• Copyright
• Contents
• Preface
• 1 Organozinc reagents and palladium
• 2 Organozinc reagents and nickel
• 3 Organozinc reagents and iron
• 4 Organozinc reagents and cobalt
• 5 Organozinc reagents and copper
• Index