Organozinc Derivatives and Transition Metal Catalysts
Formation of C-C Bonds by Cross-coupling
Janine Cossy, Janine Cossy
- 222 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Organozinc Derivatives and Transition Metal Catalysts
Formation of C-C Bonds by Cross-coupling
Janine Cossy, Janine Cossy
About This Book
Organozinc reagents are less reactive than Grignard reagents but they are much more chemoselective. Since the Negishi cross-coupling reaction developed by Ei-ichi Negishi, who was awarded the Nobel Price in chemistry in 2010, a number of cross-coupling reactions involving organozinc derivatives and transition metal catalysts (Pd, Ni, Fe, Co, Cu, âŠ) has been tuned up to form C-C bonds. This book on "Organozinc derivatives and transition metal catalysts" has been written by experts in the field and is a complement to the book entitled "Grignard reagents and transition metal catalysts" (a De Gruyter book, edited by J. Cossy).
Grignard reagents or organozinc reagents, that is the question? From a given substrate, what is the best organometallic reagent and the best transition metal to form a C-C bond by using a cross-coupling reaction? The solution might be found in these two books.