Handbook of Pharmacokinetics and Toxicokinetics
eBook - ePub

Handbook of Pharmacokinetics and Toxicokinetics

  1. 752 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Handbook of Pharmacokinetics and Toxicokinetics

About this book

This fully revised and expanded volume is an effort to blend the common approaches to pharmacokinetics and toxicokinetics. It integrates the principles held in common by both fields through a logical and systematic approach, which includes mathematical descriptions of physical and physiological processes employed in the approaches to pharmacokinetics and toxicokinetics modeling. It emphasizes general principles and concepts and related, isolated applications and case study observations. The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research, scientific or regulatory decisions, or for offering advanced courses/workshops and seminars.

Features:

  • Comprehensive handbook on principles and applications of PK/TK appealing to a diverse audience including scientists and students
  • An excellent text fully revised and fully updated for anyone interested in the theoretical and practical pharmacokinetics
  • The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research
  • Incorporates research relevant to SDGs and of interest to industrial and regulatory environmental scientists involved in chemical contamination research and regulatory decision making related to soil, water, and ocean
  • Includes sections on applications and case studies

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Yes, you can access Handbook of Pharmacokinetics and Toxicokinetics by Mehdi Boroujerdi in PDF and/or ePUB format, as well as other popular books in Medicine & Mathematics General. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2023
Print ISBN
9781032197050
eBook ISBN
9781000878479
Edition
2
Topic
Medicine
Subtopic
Mathematics General

Table of contents

  1. Cover
  2. Half-Title
  3. Title
  4. Copyright
  5. Dedication
  6. Contents
  7. Preface
  8. 1 Pharmacokinetics and Toxicokinetics
  9. 2 PK/TK Considerations of Auricular (Otic) – Buccal/Sublingual, and Ocular/Ophthalmic Routes of Administration
  10. 3 PK-TK Considerations of Nasal, Pulmonary and Oral Routes of Administration
  11. 4 PK/TK Considerations of Intra-Arterial, Intramuscular, Intraperitoneal, Intravenous, and Subcutaneous Routes of Administration
  12. 5 PK/TK Considerations of Transdermal, Intradermal, and Intraepidermal Routes of Administration
  13. 6 PK/TK Considerations of Rectal, Vaginal, and Intraovarian Routes of Administration
  14. 7 PK/TK Considerations of Absorption Mechanisms and Rate Equations
  15. 8 PK – TK Considerations of Distribution Mechanisms and Rate Equations
  16. 9 PK/TK Considerations of Xenobiotic Metabolism Mechanisms and Rate Equations
  17. 10 PK – TK Considerations of Renal Function and Elimination of Xenobiotics - Estimation of Parameters and Constants
  18. 11 Elimination Rates and Clearances (Excretion + Metabolism)
  19. 12 Approaches in PK/PD and TK/TD Mathematical Modeling
  20. 13 Practical Applications of PK/TK Models: Instantaneous Exposure to Xenobiotics - Single Intravenous Bolus Injection
  21. 14 Practical Applications of PK/TK Models: Continuous Zero‑Order Exposure to Xenobiotics - Intravenous Infusion
  22. 15 Practical Applications of PK/TK Model: First-Order Absorption via Extravascular Route - Oral Administration
  23. 16 Practical Application of PK/TK Models: Multiple Dosing Kinetics
  24. 17 Biopharmaceutics Provisions, Classifications and Mechanistic Models
  25. 18 Bioavailability, Bioequivalence, and Biosimilarity
  26. 19 Quantitative Cross-Species Extrapolation and Low-Dose Extrapolation
  27. 20 Practical Application of PK/TK Models: Population Pharmacokinetics/Toxicokinetics
  28. 21 Practical Application of Pk/TK Models: Preclinical PK/TK and Clinical Trial
  29. 22 Adjustment of Dosage Regimen in: Renal Impairment, Liver disease and Pregnancy
  30. Addendum I – Part 1: Standard Terminologies for Routes of Administration
  31. Addendum I – Part 2: Relevant Mathematical Concepts
  32. Addendum I – Part 3: Abbreviation – Glossary – PK/TK Constants and Variables
  33. Addendum II – Part 1
  34. Addendum II – Part 1
  35. Addendum II – Part 1
  36. Addendum II – Part 2
  37. Addendum II – Part 2
  38. Addendum II – Part 2
  39. Addendum II – Part 2
  40. Addendum II – Part 2
  41. Addendum II – Part 2
  42. Addendum II – Part 2
  43. Addendum II – Part 2
  44. Addendum II – Part 3
  45. Addendum II – Part 3
  46. Addendum II – Part 3
  47. Addendum II – Part 3
  48. Addendum II – Part 3
  49. Addendum II – Part 3
  50. Addendum II – Part 3
  51. Addendum II – Part 4
  52. Addendum II – Part 4
  53. Addendum II – Part 4
  54. Addendum II – Part 4
  55. Addendum II – Part 4
  56. Addendum II – Part 4
  57. Addendum II – Part 4
  58. Addendum II – Part 4
  59. Addendum II – Part 4
  60. Addendum II – Part 5
  61. Addendum II – Part 5
  62. Addendum II – Part 5
  63. Addendum II – Part 5
  64. Addendum II – Part 5
  65. Addendum II – Part 5
  66. Addendum II – Part 5
  67. Addendum II – Part 5
  68. Addendum II – Part 5
  69. Addendum II – Part 6
  70. Addendum II – Part 6
  71. Addendum II – Part 6
  72. Addendum II – Part 6
  73. Addendum II – Part 6
  74. Addendum II – Part 6
  75. Addendum II – Part 7
  76. Addendum II – Part 7
  77. Addendum II – Part 7
  78. Addendum II – Part 7
  79. Addendum II – Part 7
  80. Addendum II – Part 7
  81. Addendum II – Part 7
  82. Addendum II – Part 7
  83. Addendum II – Part 7
  84. Addendum II – Part 8
  85. Addendum II – Part 8
  86. Addendum II – Part 8
  87. Addendum II – Part 8
  88. Addendum II – Part 8
  89. Addendum II – Part 8
  90. Addendum II – Part 8
  91. Addendum II – Part 8
  92. Addendum II – Part 8
  93. Addendum II – Part 9
  94. Addendum II – Part 9
  95. Addendum II – Part 9
  96. Addendum II – Part 9
  97. Addendum II – Part 9
  98. Index