Prototype of a Biomimetic Multi-Spiked Connecting Scaffold for a New Generation of Resurfacing Endoprostheses

Ryszard Uklejewski, Piotr Rogala, Mariusz Winiecki

• Publisher: CRC Press
• Year: 2023
• Print ISBN: 9781032418445
• eBook ISBN: 9781000931556
• Edition: 1
• Topic: Technology & Engineering
• Subtopic: Biomedical Science
• Index: Technology & Engineering

The monograph comprehensively presents the research on the prototype of the biomimetic Multi-Spiked Connecting Scaffold (MSC-Scaffold) for cementless fixation of the components of a new generation of resurfacing arthroplasty (RA) endoprostheses. This research, carried out by a bioengineering-surgical team from three Polish universities, includes bioengineering design, rapid prototyping, manufacturing in selective laser melting, functionalization, surface modification, numerical studies, experimental in vitro studies, and pilot surgical experiments in an animal model.

Features:

• Presents the prototype of the multi-spiked connecting scaffold for a new generation of resurfacing endoprostheses of the knee and the hip
• Explains this prototype scaffold as the first worldwide design of the biomimetic fixation of components of diarthrodial joints resurfacing endoprostheses
• Insights into the entire process of bioengineering design and research on this novel way of resurfacing endoprostheses fixation
• Reviews main results of the scaffold prototyping and SLM manufacturing, structural and osteoconductive functionalization, and surface modification
• Reports experimental and numerical investigations of mechanical behavior of the scaffold-bone system, cell culture studies, and pilot surgical experiments in animal models

This book is aimed at professionals and graduate students in biomedical engineering, biomaterials engineering, and bone & joint surgery.

The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

Table of contents

• Cover
• Half Title
• Title Page
• Copyright Page
• Dedication
• Table of Contents
• Forewords
• Preface
• Acknowledgements
• About the authors
• Introduction
• Chapter 1 Characteristics of contemporary hip resurfacing arthroplasty endoprostheses and their possible postoperative complications
• References
• Chapter 2 Idea of entirely non-cemented implantation of the components of hip resurfacing arthroplasty endoprostheses with the multi-spiked connecting scaffold
• References
• Chapter 3 Design, rapid prototyping, and manufacturing of the biomimetic multi-spiked connecting scaffold prototype for non-cemented resurfacing endoprostheses
• Chapter 4 Structural and osteoconductive functionalization of the interspike space of the prototype multi-spiked connecting scaffold
• Chapter 5 Formation of osteoinductive and osseointegrative properties of the bone-contacting surface of the multi-spiked connecting scaffold prototype by the electrochemical cathodic deposition of calcium phosphates
• Chapter 6 Research on the system of bone and the prototype multi-spiked connecting scaffold in order to design the structural and biomechanical properties of this system
• Chapter 7 Pilot study on the prototype multi-spiked connecting scaffold for non-cemented resurfacing endoprostheses in an animal model
• Chapter 8 Pilot micro-CT study of the impact of embedding the multi-spiked connecting scaffold on the density and compressive strength of the subchondral trabecular bone of femoral heads from patients with osteoarthritis
• Chapter 9 Summary, conclusions, and final remarks
• Appendix 1 – Patents front pages scans (US, Canada, Europe)
• Appendix 2 – Letter of thanks from the Rector of the Poznan University of Technology, Poland
• Index