
- 136 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
About this book
Positron emission tomography (PET) is an important clinical tool, and with its longer half-life, copper-64 has several unique attributes that make it a multi-purpose radionuclide with many potential applications. Additionally, copper as a trace element plays a pivotal role in several human metabolic and pathologic diseases and is involved in malignant cells biochemistry pathways. This offers the opportunity for scientists to explore the theranostic capabilities of copper-64. This current publication, arising from an IAEA Coordinated Research Project, describes the biochemical and radiopharmaceutical aspects of copper-64, and its clinical applications, with specific guidelines and methods for the production of copper-64 chloride, peptide and monoclonal antibody radiopharmaceuticals. It is expected to be of use to all professionals involved in the field by specifying ideal production, formulation and quality control methods.
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Information
Table of contents
- 1. INTRODUCTION
- CONCLUSIONS
- Annex I COPPER IN LIFE
- Annex II COPPER BIOLOGY
- Annex III DETAILED PROCEDURE FOR THE DEVELOPMENT OF A 64Cu-NOTA-mAb FOR PET APPLICATIONS
- ABBREVIATIONS
- CONTRIBUTORS TO DRAFTING AND REVIEW