To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution has turned this apparent disadvantage into an opportunity for transmitting information. As a result, redox signaling within the cell is an efficient exquisitely organized process. A key element for its regulation is the physical separation of sources and targets into different cell compartments. Peroxiporins, H2O2 transporting proteins spanning biological membranes, distribute the signal from emitters to receptors. Thus, these channels are strategically situated in the thin line between life and death, guaranteeing adequate but safe signaling.

Key Features:

- Provides a brief history of the discovery and characterization of peroxiporins
- Reviews key findings on hydrogen peroxide transport across biological membranes
- Discusses the cartography of redox signaling in crowded cells
- Includes lavish illustrations and comprehensive images to facilitate teaching
- Highlights recent findings, outstanding controversies and open questions

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Yes, you can access Peroxiporins by Iria Medraño-Fernandez, Gerd Patrick Bienert, Roberto Sitia, Iria Medraño-Fernandez,Gerd Patrick Bienert,Roberto Sitia in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Biological Sciences

Subtopic

Biochemistry in Medicine

Index

Biological Sciences

Cover
Half Title
Series
Title
Copyright
Contents
Preface
Acknowledgments
Editors
Contributors
1 Role of the Cellular Hydrogen Peroxide Landscape Profile in Redox Signaling
2 How Gradients and Microdomains Determine H2O2 Redox Signaling
3 Diffusion and Transport of Peroxynitrite across Cell Membranes
4 Hydrogen Peroxide as a Substrate for Aquaporins from a Structure-Function Perspective
5 Use of Genetically Encoded Reporters to Quantify Intracellular H2O2 Levels in Eukaryotic Cells
6 H2O2/ROS Production, Consumption, and Transport across Organelles
7 The Mystery behind Hydrogen Peroxide Permeation across the Peroxisomal Membrane
8 Role of Mammalian Aquaporin inside the Cell: An Update
9 Peroxiporins in Plant-Microbial Interactions
10 Role of Peroxiporins in Plant Stress Signaling and Development
11 Evolution and Function of Peroxiporins in Piscine Spermatozoa
12 Regulated Transport of H2O2 across the Plasma Membrane by Aquaporin-8
13 Peroxiporins as Crucial Advocates of Redox Architecture
14 The History of the Discovery of Peroxiporins
Index

About this book

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Table of contents