Brain Fables
eBook - PDF

Brain Fables

The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

Brain Fables

The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them

About this book

An estimated 80 million people live with a neurodegenerative disease. That number is expected to increase rapidly as populations age, lifespans increase, and exposure to toxins rises. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. This is because diseases such as Parkinson's and Alzheimer's do not exist in biology. Yet, hundreds of clinical trials around the world are examining the potential of single therapies in thousands of people sharing one of these labels. Compounding the problem, these therapies were developed on evidence from models that do not come close to capturing the complexity of these diseases in the affected humans. These practices must end. Brain Fables is a call to refocus on understanding living and aging to create the personalized treatments each affected individual desperately needs.

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Yes, you can access Brain Fables by Alberto Espay,Benjamin Stecher in PDF and/or ePUB format, as well as other popular books in Medicine & Neurology. We have over one million books available in our catalogue for you to explore.

Information

Table of contents

  1. Cover
  2. Half-title page
  3. Title page
  4. Copyright page
  5. Dedication
  6. Contents
  7. Preface 1 – The Question
  8. Preface 2 – Enter Patient
  9. Acknowledgements
  10. Chapter 1 The Shaky Six and the “Second Reality”
  11. Chapter 2 Pieces of a Puzzle?
  12. Chapter 3 Disease “Redefinition”: A Tough Pill to Swallow
  13. Chapter 4 Disease Subtypes: The Promise and the Fallacy
  14. Chapter 5 Protein Paradox
  15. Chapter 6 The Fault in Our Models
  16. Chapter 7 Biomarkers: The Promise and the Fallacy
  17. Chapter 8 Lessons from Oncology
  18. Chapter 9 Symptomatic vs. Disease-Modifying Therapies
  19. Chapter 10 The Hypothesis That Refuses to Die
  20. Chapter 11 Our Living Dissonance
  21. Chapter 12 The Scientific and Lay Narratives
  22. Chapter 13 Challenges Viewed from Afar
  23. Chapter 14 The Moonshot: Population-Based Studies of Aging
  24. Chapter 15 Predictions for the 2020s and Beyond
  25. Epilogue: “When Will We Have a Cure for Parkinson’s Disease?”
  26. Note Added at Press Time – Reviving LOF
  27. References
  28. Index