
- English
- PDF
- Available on iOS & Android
Multiscale Modeling of the Skeletal System
About this book
Integrative approaches to biomedical research promise to advance our understanding of the human body and physiopathology of diseases. In this book, the author focuses on the skeletal system, demonstrating how multiscale modeling can determine the relationship between bone mechanics and disease. Introductory chapters explain the concept of integrative research, what a model is, predictive modeling, and the computational methods used throughout the book. Starting with whole body anatomy, physiology and modeling, subsequent chapters scale down from bone and tissue levels to the cellular level, where the modeling of mechanobiological processes is addressed. Finally, the principles are applied to address truly complex, multiscale interactions. Special attention is given to real-world clinical applications: one in pediatric skeletal oncology and one on the prediction of fracture risks in osteoporotic patients. This book has wide interdisciplinary appeal and is a valuable resource for researchers in mechanical and biomedical engineering, quantitative physiology and computational biology.
Frequently asked questions
- Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
- Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Information
Table of contents
- Cover
- Multiscale Modeling of the Skeletal System
- Title
- Copyright
- Dedication
- Contents
- Preface
- Acknowledgements
- 1 Introduction
- 2 Methodological aspects
- 3 The body level
- 4 Organ level: the bones
- 5 Tissue level: mineralized extracellular matrix
- 6 Cellular level: cell–matrix interaction
- 7 Applications of multiscale modeling
- 8 Multiscale modeling: the future
- References
- Index