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Principles of Psychiatric Genetics
About this book
Disorders of behavior represent some of the most common and disabling diseases affecting humankind; however, despite their worldwide distribution, genetic influences on these illnesses are often overlooked by families and mental health professionals. Psychiatric genetics is a rapidly advancing field, elucidating the varied roles of specific genes and their interactions in brain development and dysregulation. Principles of Psychiatric Genetics includes 22 disorder-based chapters covering, amongst other conditions, schizophrenia, mood disorders, anxiety disorders, Alzheimer's disease, learning and developmental disorders, eating disorders and personality disorders. Supporting chapters focus on issues of genetic epidemiology, molecular and statistical methods, pharmacogenetics, epigenetics, gene expression studies, online genetic databases and ethical issues. Written by an international team of contributors, and fully updated with the latest results from genome-wide association studies, this comprehensive text is an indispensable reference for psychiatrists, neurologists, psychologists and anyone involved in psychiatric genetic studies.
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Table of contents
- Cover
- Principles of Psychiatric Genetics
- Title
- Copyright
- Contents
- Contributors
- Preface
- Chapter 1 Contribution of genetic epidemiology to our understanding of psychiatric disorders
- Chapter 2 A basic overview of contemporary human genetic analysis strategies
- Chapter 3 DNA methods
- Chapter 4 In silico analysis strategies and resources for psychiatric genetics research
- Chapter 5 Gene expression studies in psychiatric disorders
- Chapter 6 Pharmacogenetics in psychiatry
- Chapter 7 Functional validation of candidate genetic susceptibility factors for major mental illnesses: From protein chemistry, cell biology, and animal studies, to human brain imaging
- Chapter 8 Epigenetic mechanisms in drug addiction and depression
- Chapter 9 Panic disorder
- Chapter 10 The genetics of the phobic disorders and generalized anxiety disorder
- Chapter 11 Genetic contributions to obsessiveācompulsive disorder (OCD) and OCD-related disorders
- Chapter 12 Post-traumatic stress disorder
- Chapter 13 Antisocial behavior: geneāenvironment interplay
- Chapter 14 Learning disabilities
- Chapter 15 Attention-deficit hyperactivity disorder
- Chapter 16 Autism and autism spectrum disorders
- Chapter 17 The genetics of bipolar disorder
- Chapter 18 The genetics of major depression
- Chapter 19 The genetics of schizophrenia
- Chapter 20 The genetics of anorexia and bulimia nervosa
- Chapter 21 Genetics and common human obesity
- Chapter 22 Alcoholism
- Chapter 23 Nicotine dependence
- Chapter 24 Human molecular genetics of opioid addiction
- Chapter 25 Genetics of stimulant dependence
- Chapter 26 Genetics of personality disorders
- Chapter 27 Ethical issues in behavioral genetics
- Chapter 28 Genetics of Tourette syndrome and related disorders
- Chapter 29 Endophenotypes in psychiatric genetics
- Chapter 30 Developmental disorders
- Chapter 31 Alzheimers disease
- Index