Chemistry and Biological Activities of Ivermectin
eBook - PDF

Chemistry and Biological Activities of Ivermectin

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

Chemistry and Biological Activities of Ivermectin

About this book

CHEMISTRY AND BIOLOGICAL ACTIVITIES OF IVERMECTIN

The book focuses on the biological activities of ivermectin as well as the significant global utility of IVM since it was first used about 35 years ago.

Ivermectin (IVM) is a "wonder drug" containing a 16-membered macrocyclic lactone ring system in its structure and derived from the family of avermectins. It was isolated by the fermentation of the soil microorganism Streptomyces avermitilis by Satoshi Omura in 1960 and studied by William C. Campbell in 1981, which allowed for its treatment of onchocerciasis (River Blindness) in Africa. Both scientists subsequently received the 2015 Nobel Prize in Physiology or Medicine. It was approved by the FDA in 1997 for the treatment of Strongyloidiasis and crusted scabies in AIDS patients. After that, IVM has attracted the tremendous attention of the scientific community and has been used for diverse purposes, including as an inhibitor of the causative virus (SARS-CoV-2).

The chief purpose of this volume is to focus on the chemistry and biological activities of ivermectin. The chapters have been arranged in a systematic manner, starting from the historical background and synthesis of IVM to the pharmacological and environmental aspects, followed by diverse applications. Although the usage of ivermectin for the treatment of COVID-19 remains under investigation and controversial, one of the chapters is dedicated to its use. The anti-parasitic, anti-malarial, anti-cancer, and anti-inflammatory activities of IVM are discussed in detail. The anthelminthic and insecticidal roles of IVM are briefly described and there are several cases of IVM in dermatology.

Audience

Researchers, scientists, and postgraduate students working in the fields of organic synthesis, medicinal chemistry, medical science, pharmacy, biotechnology and biomedical sciences.

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Yes, you can access Chemistry and Biological Activities of Ivermectin by Rashid Ali,Shahid Ul Islam,Shahid ul-Islam in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Industrial & Technical Chemistry. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Wiley-Scrivener
Year
2023
Print ISBN
9781394166541
eBook ISBN
9781394168026
Edition
1
Topic
Physical Sciences
Subtopic
Industrial & Technical Chemistry

Table of contents

  1. Cover
  2. Title Page
  3. Copyright Page
  4. Contents
  5. Preface
  6. Chapter 1 Introduction to Ivermectin
  7. Chapter 2 Historical Background of and Synthetic Approaches to Ivermectin (IVM) and its Homologues
  8. Chapter 3 Ivermectin as a Repurposed Drug for COVID-19
  9. Chapter 4 Ivermectin as an Anti-Parasitic Agent
  10. Chapter 5 Emerging Paradigm of Ivermectin and its Hybrids in Elimination of Malaria
  11. Chapter 6 Ivermectin: A Potential Repurposed Anti-Cancer Therapeutic
  12. Chapter 7 Ivermectin as an Anti-Inflammatory Agent
  13. Chapter 8 Ivermectin: An Anthelminthic and Insecticide
  14. Chapter 9 Potential Applications of Ivermectin (IVM) in Dermatology
  15. Chapter 10 Antiviral Uses of Ivermectin
  16. Chapter 11 Toxicology, Safety, and Environmental Aspects of Ivermectin
  17. Index
  18. EULA