Current Topics in Nonclinical Drug Development
eBook - ePub

Current Topics in Nonclinical Drug Development

Volume 2

  1. 471 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

About this book

The second volume in the CURRENT TOPICS IN NONCLINICAL DRUG DEVELOPMENT SERIES explores the critical issues and current topics in nonclinical drug development. This second volume covers individual topics and strategies in drug development from compound characterization to drug registration. Written by a variety of experts in the field, recent and rapid advances in technologies and associated changes in regulatory guidance are discussed.

Select topics include:

  • Evolution of Artificial Intelligence (AI) technologies and the impact on toxicologic pathology.
  • Current approaches to carcinogenicity testing.
  • Predicting drug-drug interactions.
  • Current understanding of idiosyncratic drug reaction.
  • Assessing cardiovascular risks beyond QT interval.
  • Use of 3D cell cultures in toxicology and ADME.
  • Development of small molecule-antibody complexes.
  • Differentiating adverse from non-adverse findings in nonclinical studies.

Current Topics in Nonclinical Drug Development: Volume 2 will aid toxicologists, toxicologic pathologists, consultants, regulators, study directors, and nonclinical scientists dealing with day-to-day issues encountered in drug development and assist in formulating strategies for resolution of these issues. In addition, the book will be a valuable reference for academicians and graduate students pursuing research related to nonclinical drug development.

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Yes, you can access Current Topics in Nonclinical Drug Development by Philip Bentley, Pritam S. Sahota, Zbigniew Wojcinski, Philip Bentley,Pritam S. Sahota,Zbigniew Wojcinski in PDF and/or ePUB format, as well as other popular books in Scienze fisiche & Biologia. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2023
Print ISBN
9780367466688
eBook ISBN
9781000961140
Edition
1
Subtopic
Biologia

Table of contents

  1. Cover
  2. Half Title Page
  3. Series Page
  4. Title Page
  5. Copyright Page
  6. Table of Contents
  7. Preface
  8. Acknowledgments
  9. About the Editors
  10. Contributors
  11. 1 Introduction and History of Digital Toxicologic Pathology
  12. 2 Carcinogenicity Testing of Human Pharmaceuticals
  13. 3 Differentiating Adverse and Non-Adverse Findings in Non-Clinical Studies
  14. 4 Current Understanding of Idiosyncratic Drug Reactions
  15. 5 Three-Dimensional Cell Culture Models in Toxicology and ADME
  16. 6 Assessing Cardiovascular Risk Beyond the hERG Channel and the QT Interval
  17. 7 Fundamentals of Drug–Drug Interactions
  18. 8 Development of Antibody-Drug Conjugates (ADCs)
  19. Index