Microbial biofilm plays an important role in the life cycle of microorganisms surviving in diverse and harsh environments such as extremes of temperatures, pH, salinity, nutrient scarcity etc. Biofilm formation is a survival strategy adopted by microorganisms allowing colonization in new niches by dispersal of microbes from the microbial clusters embedded within an outer polymer layer produced by the microorganism itself. This layer comprises of extracellular polymeric substances (EPS) that helps the indwelling microbes to grow and divide in a protected environment against invaders like antimicrobial agents, surfactant, biocides and phagocytic cells of host organisms. Thus, EPS matrix prevents the penetration of antimicrobials thereby allowing the indwelling microbes to survive and give rise to antimicrobial resistance posing threat to human health.

The present book highlights a detailed analysis of the mechanism of biofilm formation in both Gram positive and Gram-negative bacteria and the role of quorum sensing signaling mechanism in the genetic regulation pathway.

The book titled "Natural Products: Alternative therapeutics as Quorum Sensing (QS) inhibitors" provides a detailed and systematic review of mechanism of quorum sensing in both Gram positive and Gram-negative bacteria and alternative pharmacological developments as a potent solution to the rise of antimicrobial resistance during biofilm formation.

Features:

A systematic overview of the mechanism of quorum sensing in the development of microbial biofilms
Biofilm formation and its role in the emergence of antimicrobial resistance
Recent pharmacological development of antibiofilm remedies involving biogenic compounds

This book serves as a reference book for researchers investigating the progression of events during microbial biofilm formation starting from the genetic cascade regulating quorum sensing to secretion of autoinducers and design of safer methodologies for the successful eradication of microbial biofilm. It may also be used as a textbook for a undergraduate level course in microbiology or microbial biotechnology.

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Yes, you can access Natural Products by Moupriya Nag, Dibyajit Lahiri, Jaideep Banerjee, Taniya Roy Chowdhury, Moupriya Nag,Dibyajit Lahiri,Jaideep Banerjee,Taniya Roy Chowdhury in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Biological Sciences

Subtopic

Biology

Index

Biological Sciences

Cover
Half Title
Series
Title
Copyright
Contents
Preface
Editor Biographies
List of Contributors
Chapter 1 Introduction
Chapter 2 Quorum Sensing in Gram-Positive Bacteria
Chapter 3 Quorum Sensing in Gram-Negative Bacteria
Chapter 4 Fundamentals of Bacterial Quorum Sensing and Antimicrobial Resistance
Chapter 5 Phytocompound-Mediated Inhibition of Quorum-Sensing Cascade in Pathogenic Bacteria
Chapter 6 Microbiologically Synthesized Nanoparticles in Inhibition of Quorum Sensing
Chapter 7 Plant-Mediated Synthesized Nanoparticles in Down-Regulating Quorum Sensing
Chapter 8 Fungal Compounds in Down-Regulating Quorum Sensing
Chapter 9 Antimicrobial Peptides: Sources, Types, and Antibiofilm Activity
Chapter 10 Algal Compounds in Down-Regulating Quorum Sensing of Biofilm
Chapter 11 Microbial Volatile Organic Compounds as Quorum Quenchers

About this book

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Table of contents