
Cardiovascular Beta Adrenergic Responses
UCLA Forum in Medical Sciences - Number 13
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Cardiovascular Beta Adrenergic Responses
UCLA Forum in Medical Sciences - Number 13
About this book
This volume, Cardiovascular Beta Adrenergic Responses, compiles the proceedings of a pivotal conference held in February 1968, sponsored by the UCLA School of Medicine and University of California Extension, with support from Ayerst Laboratories. The conference brought together leading researchers to present and discuss the groundbreaking developments in the understanding and clinical application of beta adrenergic stimulation and blockade, particularly at a time when the potent beta blocker propranolol was about to be introduced for widespread clinical use. The symposium addressed both the basic scientific aspects of beta adrenergic function and its clinical implications. On the first day, experts explored the mechanisms of beta adrenergic stimulation and blockade in the heart and peripheral vessels, featuring important discussions on the electrophysiological effects of catecholamines and preliminary findings on their role in cardiac function. The second day focused on clinical outcomes, highlighting the effectiveness of beta blockers in treating arrhythmias, angina pectoris, and hypertrophic cardiomyopathy. Propranolol's therapeutic potential, especially its rapid impact on ischemic symptoms, was underscored throughout the proceedings. This volume not only reflects on the progress made in cardiovascular pharmacology but also honors the pioneering work of Dr. Raymond P. Ahlquist, whose alpha-beta hypothesis laid the foundation for these transformative advances. This title was originally published in 1970.
This volume, Cardiovascular Beta Adrenergic Responses, compiles the proceedings of a pivotal conference held in February 1968, sponsored by the UCLA School of Medicine and University of California Extension, with support from Ayerst Laboratories. The conf
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Table of contents
- Cover
- Title
- Copyright
- CONTENTS 1
- BETA ADRENERGIC BLOCKADE An Historical Review and Evaluation4 NEIL C. MORAN
- EFFECT OF PROPRANOLOL AND ITS DEXTRO-ISOMER ON EXPERIMENTALLY INDUCED ARRHYTHMIAS9 BENEDICT R. LUCCHESI, LEIGHTON S. WHITSITTt and TEIJIIWAMI»
- EFFECTS OF BETA ADRENERGIC STIMULATION AND BLOCKADE ON MYOCARDIAL MECHANICS JAN KOCH-WESER10
- EFFECT OF PROPRANOLOL ON MYOCARDIAL AUTOMATICITY AND CONTRACTILITY IN CONSCIOUS DOGS WITH CHRONIC COMPLETE HEART BLOCK11 HERBERT D. RUTTENBERG, ROGER A. HURWITZ, MARTA I. BLESA and STANLEY J. PAPPELBAUM
- PANEL DISCUSSION* Neil C. Moran, CHAIRMAN; Albert A. Kattus, Jan Koch-Weser and Benedict R. Lucchesi
- ADRENERGIC MECHANISMS IN HEART FAILURE CHARLES A. CHIDSEY and JOHN H. K. VOGEL
- EFFECTS OF CATECHOLAMINES ON SPLANCHNIC BLOOD FLOW BEFORE AND AFTER BETA ADRENERGIC BLOCKADE1213 GORDON ROSS
- EFFECT OF PROPRANOLOL ON CORONARY HEMODYNAMICS IN THE UNANESTHETIZED DOG15 BERTRAM PITT
- THE CARDIOVASCULAR AND RENAL ACTIONS OF DOPAMINE: THE QUESTION OF A SPECIFIC DOPAMINE RECEPTOR16 LEON I. GOLDBERGt and JOHN L. McNAY*
- PANEL DISCUSSION17 Gordon Ross, CHAIRMAN; Charles A. Chidsey, Leon I. Goldberg and Bertram Pitt
- CIRCULATORY EFFECTS AND CLINICAL APPLICATIONS OF BETA ADRENERGIC RECEPTOR INHIBITION STEPHEN E. EPSTEIN and EUGENE BRAUN WALD 20
- EFFECTS OF PROPRANOLOL IN THE DISEASED HEART21 STEVEN WOLFSON and RICHARD GORLIN
- THE ROLE OF BETA ADRENERGIC STIMULATION IN OBSTRUCTIVE CARDIOMYOPATHY AND ITS MODIFICATION BY BLOCKING DRUGS AND SURGERY JOHN F. GOODWIN25
- USE OF PROPRANOLOL IN THE MANAGEMENT OF CARDIAC ARRHYTHMIAS26 DONALD C. HARRISON, JOHN S. SCHROEDER, RALPH GIANELLY and ROBERT DEBUSK
- EFFECT OF PROPRANOLOL AND NITROGLYCERIN ON EXERCISE TOLERANCE IN ANGINA PECTORIS29 REX N. MACALPIN, ANTHONY B. ALVARO and ALBERT A. KATTUS
- PANEL DISCUSSION* Albert A. Kattus, CHAIRMAN; Stephen E. Epstein, Donald C. Harrison, Geoffrey HouAtt, Rex N. MacAlpin, Leo Schamroth and Steven Wolfson
- THE ROLE OF PROPRANOLOL IN THE MANAGEMENT OF ACUTE MYOCARDIAL INFARCTION31 RICHARD L. KAHLER, STUART J. BRILL and WILLIAM E. PERKINS
- USE OF BETA ADRENERGIC BLOCKADE IN HYPERTENSIVE DISEASES32 EDWARD D. FROHLICH, ROBERT C. TARAZI and HARRIET P. DUSTAN
- BETA ADRENERGIC BLOCKADE IN PEDIATRIC CARDIOLOGY GORDON R. CUMMING
- REVERSIBILITY OF NONISCHEMIC POSTURAL AND EXERCISE- INDUCED ECG ABNORMALITIES OF THE T WAVE AND ST SEGMENTS BY BETA ADRENERGIC BLOCKADE33 ALBERT A. KATTUS, REX N. MACALPIN and ANTHONY ALVARO
- PANEL DISCUSSION34 Rex N. MacAlpin, CHAIRMAN, Gordon R. Cumming, Edward D. Fröhlich, Richard L. Kahler and Albert A. Kattus
- CLINICAL ANNOTATIONS ON BETA ADRENERGIC BLOCKADE THERAPY AND SOME WARNINGS ALBERT A. KATTUS
- NAME INDEX
- SUBJECT INDEX