eBook - ePub

The Ontology of Physics for Biology

Name: The Ontology of Physics for Biology
ISBN: 9780429892325

Semantic Modeling of Multiscale, Multidomain Physiological Systems

Daniel L. Cook,

John H. Gennari,

Maxwell L. Neal,

English
ePUB (mobile friendly)
Available on iOS & Android

eBook - ePub

The Ontology of Physics for Biology

Semantic Modeling of Multiscale, Multidomain Physiological Systems

Daniel L. Cook,

John H. Gennari,

Maxwell L. Neal,

About this book

This book introduces semantic representations of multiscale, multidomain physiological systems that link to qualitative reasoning and to quantitative analysis of biophysical processes in health and disease. Two major public health problems, diabetes and hypertension, serve as use-cases to illustrate the depth and rigor of such representations for logical inference and quantitative analysis. Central to this approach is the Ontology of Physics for Biology (OPB) that formally represents the foundations of classical physics and engineering system dynamics that are the basis for our understanding of biomedical entities, processes, and functional relationships.

Furthermore, we introduce OPB-based software for annotating and abstracting available biosimulation models for reuse, recombination, and for archiving of physics-based biomedical knowledge. We have formalized and leveraged physics-based biological knowledge as a working view of physiology and biophysics from three distinct perspectives: (1) biologists and biomedical investigators, (2) biophysicists and bioengineers, and (3) biomedical ontologists and informaticists. We present a logical and intuitive semantics of classical physics as a tool for mediating and translating biophysical knowledge among biomedical domains.

Daniel L. Cook, MD, PhD

John H. Gennari, PhD

Maxwell L. Neal, PhD

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Yes, you can access The Ontology of Physics for Biology by Daniel L. Cook,John H. Gennari,Maxwell L. Neal in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biotechnology. We have over one million books available in our catalogue for you to explore.