Hematopoiesis
Biochemical, Cellular, Molecular, and Genomic Perspectives
- 288 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
About this book
This new volume discusses the widespread concerns of hematopoietic challenges in different and emerging ways. With chapters written by faculty and researchers from prestigious institutions working directly in hematopoiesis and advanced areas of biology, the volume offers a comprehensive overview of the regulation of blood cell development, epigenetic mechanisms, and regulatory non-coding RNAs. It presents concepts related to regulation of hematopoietic stem cell development, as well as survival, proliferation, and differentiation. It also discusses the microenvironmental niche where stem cells exist and develop into distinct blood cell types. A model system used to study non-coding RNA functions along with transformation of normal cells into cancer cell is elaborated on as well.
Key features of the book:
- Details how to utilize the available investigative tools and techniques to isolate and study single blood cells in different model systems
- Discusses the epigenetics of hematopoiesis
- Considers the clinical outcomes of defective hematopoiesis
- Describes hematopoiesis and cancer stem cells
- Looks at hematopoiesis in relation to specific diseases, such as minimal residual disease (MRD) and leukemia
This book provides valuable information related to developments in hematopoiesis that will be helpful for understanding the basics of hematopoiesis and the clinical treatment of blood diseases. Hematopoiesis: Biochemical, Cellular, Molecular, and Genomic Perspectives will be valuable to clinicians, medical school students, and researchers working in hematology.
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Information
Table of contents
- Cover
- Half Title
- Title
- Copyright
- Series
- Other Books from AAP
- About the Editor
- Contents
- Contributors
- Abbreviations
- Foreword
- Preface
- 1. Unravelling the Mechanism of Zebrafish Hematopoiesis: A Novel Approach
- 2. Investigative Tools to Study Blood Cells: A Focus on Single Cell Isolation and Analysis
- 3. Evaluation of Chitosan and Its Derivatives in Immunomodulating Blood Sentinel Cells
- 4. Proteoglycans and Glycosaminoglycans Regulating Functions of the Hematopoietic Stem Cell Niche
- 5. Epigenetics of Hematopoiesis: Role of HATS and HDACs
- 6. Systems Biology Approaches Toward Understanding Human Long Noncoding RNA in Hematopoietic Cells
- 7. Clinical Outcomes of Defective Hematopoiesis
- 8. Circulating Messengers of Blood and Their Clinical Applications
- 9. Hematopoiesis and Cancer Stem Cells: The Seed and the Soil Crosstalk
- 10. lncRNAs in Leukemia
- 11. Minimal Residual Disease (MRD) as a Prognostic Marker in Acute Myeloid Leukemia
- Index