Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 1

Steven Nolan, Catherine Cazin, Steven Nolan, Catherine Cazin

• Publisher: Thieme Chemistry
• Year: 2017
• Edition: 1
• eBook ISBN:
  9783132013216
• Topic: Physical Sciences
• Subtopic: Organic Chemistry

The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.

Table of contents

• Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis 1
• Title Page
• Imprint
• Preface
• Science of Synthesis Reference Library
• Volume Editors Preface
• Abstracts
• Overview
• Table of Contents
• 1.1 Introduction to N-Heterocyclic Carbenes
• 1.2 Cross Coupling
• 1.3 C-H Bond Functionalization
• 1.4 Addition Reactions
• Keyword Index
• Author Index
• Abbreviations