Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 2

Steven Nolan, Catherine Cazin, Steven Nolan, Catherine Cazin

• Publisher: Thieme Chemistry
• Year: 2017
• Print ISBN: 9783132414013
• eBook ISBN: 9783132414020
• Edition: 1
• Topic: Physical Sciences
• Subtopic: Organic Chemistry

The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis" presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.

Table of contents

• Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis 2
• Title Page
• Copyright
• Preface
• Science of Synthesis Reference Library
• Volume Editors Preface
• Abstracts
• Overview
• Table of Contents
• 2.1 Alkene Metathesis
• 2.2 Polymerization, Oligomerization, and Telomerization Involving N-Heterocyclic Carbenes as Ligands or Initiators
• 2.3 Cyclization Reactions
• 2.4 N-Heterocyclic Carbenes in Asymmetric Transition-Metal Catalysis
• 2.5 Transition-Metal-Catalyzed Oxidations
• 2.6 Carboxylation, Carbonylation, and Dehalogenation
• 2.7 Recyclable Systems
• 2.8 Recent Advances in N-Heterocyclic Carbene Organocatalysis
• Keyword Index
• Author Index
• Abbreviations