Pain
eBook - PDF

Pain

Current Understanding, Emerging Therapies, and Novel Approaches to Drug Discovery

  1. 968 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Pain

Current Understanding, Emerging Therapies, and Novel Approaches to Drug Discovery

About this book

This reference presents a detailed overview of approaches and techniques in the management of pain caused by tissue, nerve and central nervous system injuries, categorizing pain into a variety of syndromes and underlying mechanisms to aid the development of interventional pharmacologic measures.

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Yes, you can access Pain by Chas Bountra,Rajesh Munglani,William K. Schmidt in PDF and/or ePUB format, as well as other popular books in Medicine & Anesthesiology & Pain Management. We have over one million books available in our catalogue for you to explore.

Information

Table of contents

  1. Front Cover
  2. Title Page
  3. Preface
  4. Contents
  5. Chapter 1- Mechanism-Based Classifications of Painand Analgesic Drug Discovery
  6. Chapter 2- Sites of Analgesic Action
  7. Chapter 3- From Acute to Chronic Pain Peripheral and Central Mechanisms
  8. Chapter 4- Central and Peripheral Components of Neuropathic Pain
  9. Chapter 5- A New Perspective on Signal Transduction in Neuropathic Pain
  10. Chapter 6- Pain and the Somatosensory Cortex
  11. Chapter 7- Descending Pathways in Spinal Cord Stimulation and Pain Control
  12. Chapter 8- Local Neuroimmune Interactions in Visceral Hyperalgesia
  13. Chapter 9- Pain Processing in the Periphery
  14. Chapter 10- Neuroimaging of Pain
  15. Chapter 11- Surrogate Models of Pain
  16. Chapter 12- Acute Trauma and Postoperative Pain
  17. Chapter 13- Effectiveness of Needling Techniques with Special Reference to Myofascial Pain Syndromes
  18. Chapter 14- Advances in the Management of Spinal Pain and Radiofrequency Techniques
  19. Chapter 15- Pulsed Radiofrequency Treatment of Chronic Neck, Back, Sympathetic, and Peripheral Neuroma-Derived Pain
  20. Chapter 16- Spinal Cord Stimulation
  21. Chapter 17- Spinal Endoscopy
  22. Chapter 18- Cancer Pain Treatment
  23. Chapter 19- Inflammatory Joint Disease and Pain
  24. Chapter 20- Chronic Nonmalignant Visceral Pain Syndromes of the Abdomen, Pelvis, and Bladder and Chronic Urogenital and Rectal Pain
  25. Chapter 21- Nerve Injury Pain
  26. Chapter 22- Sympathetically Maintained Pain
  27. Chapter 23- Headache
  28. Chapter 24- Psychological Factors in Measurement of Pain
  29. Chapter 25- Challenges and Pitfalls of Clinical Trials
  30. Chapter 26- Molecular Approaches to the Study of Pain
  31. Chapter 27- Molecular Validation of Pain Targets
  32. Chapter 28- Genetics of Pain
  33. Chapter 29- Animal Models of Pain
  34. Chapter 30- An Overview of Current and Investigational Drugs for the Treatmentof Acute and Chronic Pain
  35. Chapter 31- Novel Mu, Delta, and Kappa Agonists
  36. Chapter 32- Delta-Receptor, Nonpeptide Agonists
  37. Chapter 33- Peripheral Opioid Analgesia
  38. Chapter 34- Profile of ADL 2-1294, an Opioid Antihyperalgesic Agent with Selectivity for Peripheral Mu-Opiate Receptors
  39. Chapter 35- Controlled-Release Opioids
  40. Chapter 36- NMDA-Receptor Antagonists as Enhancers of Analgesic Activity
  41. Chapter 37- CCK Antagonist Potentiation of Opioid Analgesia
  42. Chapter 38- Profile of NSAID + Opioid Combination Analgesics
  43. Chapter 39- NSAIDs and COX-2 Inhibitors
  44. Chapter 40- COX-2-Specific Inhibitors
  45. Chapter 41- NK Receptor Antagonists
  46. Chapter 42- Vanilloids
  47. Chapter 43- The Development of Bradykinin Antagonistsas Therapeutic Agents
  48. Chapter 44- The Treatment of Neuropathic Pain
  49. Chapter 45- N-Methyl-D-Aspartate (NMDA) Receptors as a Target for Pain Therapy
  50. Chapter- Profile of Ketamine, CPP, Dextromethorphan, and Memantine
  51. Chapter 47- GV 196771 A, a New Glycine Site Antagonist of the NMDA Receptor with Potent Antihyperalgesic Activity
  52. Chapter 48- Voltage-Gated Sodium Channels and Pain
  53. Chapter 49- Calcium Channel Antagonists and the Control of Pain
  54. Chapter 50- Profile of Ziconotide (SNX-111)
  55. Chapter 51- Nitric Oxide Synthase Inhibitors and the Role of Nitric Oxide in Nociception
  56. Chapter 52- Adenosine and Pain
  57. Chapter 53- Adenosine Kinase Inhibition as a Therapeutic Approach to Analgesia
  58. Chapter 54- P2X Purinergic Receptors for ATP in Nociception
  59. Chapter 55- Somatostatin Receptors in Analgesia
  60. Chapter 56- Cannabinoids
  61. Chapter 57- Antinociceptive Effects of Centrally Administered Neurotrophic Factors
  62. Chapter 58- Peripheral Neurotrophic Factors and Pain
  63. Chapter 59- Profile of Tramadol and Tramadol Analogues
  64. Chapter 60- Sumatriptan and Related 5-HT1B/ 1D Receptor Agonists
  65. Chapter 61- Cholinergic Approaches to Pain Therapy
  66. Chapter 62- Analgesic Effects of Vedaclidine, a Mixed Agonist-Antagonist at Muscarinic Receptor Subtypes
  67. Chapter 63- Gabapentin and Related Compounds
  68. Chapter 64- The Role of Gabapentin in the Management of Neuropathic Pain
  69. Chapter 65- New Local Anesthetic Analgesics
  70. Chapter 66- Spinal Adrenergic Agonists for Intractable Cancer Pain
  71. Chapter 67- Cellular Implantation for the Treatmentof Chronic Pain
  72. Chapter 68- Bone-Seeking Radiopharmaceuticalsto Palliate Painful Bone Metastases
  73. Appendix I: Currently Marketed Analgesics(U.S.A.; 1998-2001)
  74. Appendix II: 21-Year Survey of Analgesicsin Development for Treatment of Acuteor Chronic Pain
  75. Further Readings
  76. Index
  77. Back Cover