
eBook - PDF
Pain
Current Understanding, Emerging Therapies, and Novel Approaches to Drug Discovery
- 968 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Pain
Current Understanding, Emerging Therapies, and Novel Approaches to Drug Discovery
About this book
This reference presents a detailed overview of approaches and techniques in the management of pain caused by tissue, nerve and central nervous system injuries, categorizing pain into a variety of syndromes and underlying mechanisms to aid the development of interventional pharmacologic measures.
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Yes, you can access Pain by Chas Bountra,Rajesh Munglani,William K. Schmidt in PDF and/or ePUB format, as well as other popular books in Medicine & Anesthesiology & Pain Management. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- Title Page
- Preface
- Contents
- Chapter 1- Mechanism-Based Classifications of Painand Analgesic Drug Discovery
- Chapter 2- Sites of Analgesic Action
- Chapter 3- From Acute to Chronic Pain Peripheral and Central Mechanisms
- Chapter 4- Central and Peripheral Components of Neuropathic Pain
- Chapter 5- A New Perspective on Signal Transduction in Neuropathic Pain
- Chapter 6- Pain and the Somatosensory Cortex
- Chapter 7- Descending Pathways in Spinal Cord Stimulation and Pain Control
- Chapter 8- Local Neuroimmune Interactions in Visceral Hyperalgesia
- Chapter 9- Pain Processing in the Periphery
- Chapter 10- Neuroimaging of Pain
- Chapter 11- Surrogate Models of Pain
- Chapter 12- Acute Trauma and Postoperative Pain
- Chapter 13- Effectiveness of Needling Techniques with Special Reference to Myofascial Pain Syndromes
- Chapter 14- Advances in the Management of Spinal Pain and Radiofrequency Techniques
- Chapter 15- Pulsed Radiofrequency Treatment of Chronic Neck, Back, Sympathetic, and Peripheral Neuroma-Derived Pain
- Chapter 16- Spinal Cord Stimulation
- Chapter 17- Spinal Endoscopy
- Chapter 18- Cancer Pain Treatment
- Chapter 19- Inflammatory Joint Disease and Pain
- Chapter 20- Chronic Nonmalignant Visceral Pain Syndromes of the Abdomen, Pelvis, and Bladder and Chronic Urogenital and Rectal Pain
- Chapter 21- Nerve Injury Pain
- Chapter 22- Sympathetically Maintained Pain
- Chapter 23- Headache
- Chapter 24- Psychological Factors in Measurement of Pain
- Chapter 25- Challenges and Pitfalls of Clinical Trials
- Chapter 26- Molecular Approaches to the Study of Pain
- Chapter 27- Molecular Validation of Pain Targets
- Chapter 28- Genetics of Pain
- Chapter 29- Animal Models of Pain
- Chapter 30- An Overview of Current and Investigational Drugs for the Treatmentof Acute and Chronic Pain
- Chapter 31- Novel Mu, Delta, and Kappa Agonists
- Chapter 32- Delta-Receptor, Nonpeptide Agonists
- Chapter 33- Peripheral Opioid Analgesia
- Chapter 34- Profile of ADL 2-1294, an Opioid Antihyperalgesic Agent with Selectivity for Peripheral Mu-Opiate Receptors
- Chapter 35- Controlled-Release Opioids
- Chapter 36- NMDA-Receptor Antagonists as Enhancers of Analgesic Activity
- Chapter 37- CCK Antagonist Potentiation of Opioid Analgesia
- Chapter 38- Profile of NSAID + Opioid Combination Analgesics
- Chapter 39- NSAIDs and COX-2 Inhibitors
- Chapter 40- COX-2-Specific Inhibitors
- Chapter 41- NK Receptor Antagonists
- Chapter 42- Vanilloids
- Chapter 43- The Development of Bradykinin Antagonistsas Therapeutic Agents
- Chapter 44- The Treatment of Neuropathic Pain
- Chapter 45- N-Methyl-D-Aspartate (NMDA) Receptors as a Target for Pain Therapy
- Chapter- Profile of Ketamine, CPP, Dextromethorphan, and Memantine
- Chapter 47- GV 196771 A, a New Glycine Site Antagonist of the NMDA Receptor with Potent Antihyperalgesic Activity
- Chapter 48- Voltage-Gated Sodium Channels and Pain
- Chapter 49- Calcium Channel Antagonists and the Control of Pain
- Chapter 50- Profile of Ziconotide (SNX-111)
- Chapter 51- Nitric Oxide Synthase Inhibitors and the Role of Nitric Oxide in Nociception
- Chapter 52- Adenosine and Pain
- Chapter 53- Adenosine Kinase Inhibition as a Therapeutic Approach to Analgesia
- Chapter 54- P2X Purinergic Receptors for ATP in Nociception
- Chapter 55- Somatostatin Receptors in Analgesia
- Chapter 56- Cannabinoids
- Chapter 57- Antinociceptive Effects of Centrally Administered Neurotrophic Factors
- Chapter 58- Peripheral Neurotrophic Factors and Pain
- Chapter 59- Profile of Tramadol and Tramadol Analogues
- Chapter 60- Sumatriptan and Related 5-HT1B/ 1D Receptor Agonists
- Chapter 61- Cholinergic Approaches to Pain Therapy
- Chapter 62- Analgesic Effects of Vedaclidine, a Mixed Agonist-Antagonist at Muscarinic Receptor Subtypes
- Chapter 63- Gabapentin and Related Compounds
- Chapter 64- The Role of Gabapentin in the Management of Neuropathic Pain
- Chapter 65- New Local Anesthetic Analgesics
- Chapter 66- Spinal Adrenergic Agonists for Intractable Cancer Pain
- Chapter 67- Cellular Implantation for the Treatmentof Chronic Pain
- Chapter 68- Bone-Seeking Radiopharmaceuticalsto Palliate Painful Bone Metastases
- Appendix I: Currently Marketed Analgesics(U.S.A.; 1998-2001)
- Appendix II: 21-Year Survey of Analgesicsin Development for Treatment of Acuteor Chronic Pain
- Further Readings
- Index
- Back Cover