
- 560 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Cell Death During HIV Infection
About this book
In an effort to go beyond immune-based therapies, researchers are now considering the implications of apoptosis dysregulation during HIV-induced immunodeficiency. This work provides the first comprehensive compendium of the progress made in understanding the process of cell death related to HIV and the potential breakthroughs in treatment that offer much promise. Combining the work of more than two-dozen top researchers, this seminal volume provides clinicians and researchers with an excellent reference, while also serving as an incubator to stimulate future research. It explains the fundamental biology involved with apoptosis, explains its clinical impact in HIV, and examines the newest therapeutic approaches.
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Cell Death During HIV Infection by Andrew D. Badley in PDF and/or ePUB format, as well as other popular books in Medicine & Immunology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- Editor
- Contributors
- Introduction
- Table of Contents
- 1. Lentiviral Biology and Cell Death
- 2. Regulation of Apoptosis
- 3. Approaches Used to Detect Apoptosis
- 4. Consequences of HIV Infection on Thymus Function and T Cell Development
- 5. Deadly Intentions: Apoptosis in the Peripheral Immune System
- 6. Cell Death in HIV Infection: gp120
- 7. Vpr
- 8. Interference of the Nef Protein of HIV-1 with Pro and Antiapoptotic Pathways of T Cells
- 9. HIV-1 Tat and Apoptotic Death
- 10. HIV Protease (PR) and Cell Death
- 11. Immune Activation
- 12. Impairment of HIV-Specific Immune Effector Cell Function
- 13. Mechanisms of HIV-Infected vs. Uninfected T Cell Killing
- 14. Elevated Apoptosis of CD8+T Lymphocytes during HIV-1 Infection
- 15. Autologous Cell-Mediated Killing
- 16. Molecular Mechanisms of HIV-1 Syncytial Apoptosis
- 17. Nonapoptotic HIV-Induced T Cell Death
- 18. Apoptosis in Organ Culture and Animal Models of HIV Disease
- 19. T Cell Dynamics and the Role of Apoptosis in HIV Infection
- 20. Alteration of the Apoptotic Pathways in the Thymus during HIV Infection
- 21. Correlations between Apoptosis and HIV Disease Progression
- 22. HIV-1 Infection and Cell Death in the Nervous System
- 23. Involvement of Apoptosis in Complications of HIV and Its Treatment
- 24. Apoptosis as a Pathogenic Mechanism of HIV-Associated Opportunistic Infections
- 25. Direct Effects of Anti-HIV Therapeutics on Apoptosis
- 26. HIV-1 Reservoirs and Residual Viral Replication during Highly Active Antiretroviral Therapy
- 27. Therapeutic Approaches to Modulation of Cell Death (non-HIV)
- 28. Immunotherapy of HIV Disease
- Back Cover