Clinical Trials
eBook - PDF

Clinical Trials

A Methodologic Perspective

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

Clinical Trials

A Methodologic Perspective

About this book

Comprehensive resource presenting methods essential in planning, designing, conducting, analyzing, and interpreting clinical trials

The Fourth Edition of Clinical Trials builds on the text's reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials, discussing principles of design for various types of clinical trials and elements of planning the experiment, assembling a study cohort, assessing data, and reporting results.

Each chapter contains an introduction and summary to reinforce key points. Discussion questions stimulate critical thinking and help readers understand how they can apply their newfound knowledge.

Written by a highly qualified author with significant experience in the field, the Fourth Edition of Clinical Trials approaches the topic with:

  • Problems that may arise during a trial, and accompanying common sense solutions
  • Design alternatives for addressing many questions in therapeutic development
  • Statistical principles with new and provocative topics, such as generalizing results, operating characteristics, trial issues during the COVID-19 pandemic, and more
  • Alternative medicine, ethics, middle development, comparative studies, adaptive designs, and clinical trials using point of care data
  • Revamped exercise sets, updated and extensive references, new material on endpoints and the developmental pipeline, and revisions of numerous sections, tables, and figures

Standing out due to its accessible and broad coverage of statistical design methods which are the building blocks of clinical trials and medical research, Clinical Trials is an essential learning aid on the subject for undergraduate and graduate clinical trials courses.

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Yes, you can access Clinical Trials by Steven Piantadosi in PDF and/or ePUB format, as well as other popular books in Mathematics & Probability & Statistics. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Wiley
Year
2024
Print ISBN
9781394195664
eBook ISBN
9781394195688

Table of contents

  1. Cover
  2. Title Page
  3. Copyright
  4. Contents
  5. Preface
  6. About the Companion Website
  7. Chapter 1 Preliminaries
  8. Chapter 2 Clinical Trials as Research
  9. Chapter 3 Why Clinical Trials Are Ethical
  10. Chapter 4 Contexts for Clinical Trials
  11. Chapter 5 Measurement
  12. Chapter 6 Random Error and Bias
  13. Chapter 7 Statistical Perspectives
  14. Chapter 8 Experiment Design in Clinical Trials
  15. Chapter 9 Trial Cohorts
  16. Chapter 10 Development Paradigms
  17. Chapter 11 Translational Clinical Trials
  18. Chapter 12 Early Development and Dose Finding
  19. Chapter 13 Middle Development
  20. Chapter 14 Comparative Trials
  21. Chapter 15 Adaptive Design Features
  22. Chapter 16 Precision, Sample Size, and Power
  23. Chapter 17 Treatment Allocation
  24. Chapter 18 Monitoring Treatment Effects
  25. Chapter 19 Counting Subjects and Events
  26. Chapter 20 Estimating Clinical Effects
  27. Chapter 21 Generalizing Results From Clinical Trials
  28. Chapter 22 Prognostic Factor Analyses
  29. Chapter 23 Factorial Designs
  30. Chapter 24 Crossover Designs
  31. Chapter 25 Operating Characteristics
  32. Chapter 26 Meta‐Analyses
  33. Chapter 27 Reporting and Authorship
  34. Chapter 28 Misconduct and Fraud in Clinical Research
  35. Chapter 29 Clinical Trials in the COVID‐19 Pandemic
  36. Chapter 30 Real‐World Clinical Trials
  37. Appendix A Notation and Terminology
  38. References
  39. Index
  40. EULA