Pharmaceutical Preformulation and Formulation

A Practical Guide from Candidate Drug Selection to Commercial Dosage Form

Mark Gibson

• Publisher: CRC Press
• Year: 2016
• Print ISBN:
  9781420073171
• eBook ISBN:
  9781040068939
• Topic: Technology & Engineering
• Subtopic: Pharmacology
• Index: Technology & Engineering

Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form reflects the mounting pressure on pharmaceutical companies to accelerate the new drug development and launch process, as well as the shift from developing small molecules to the growth of biopharmaceuticals. The book meets the need for advanced information for drug preformulation and formulation and addresses the current trends in the continually evolving pharmaceutical industry.

Topics include:

• Candidate drug selection



• Drug discovery and development



• Preformulation predictions and drug selections



• Product design to commercial dosage form



• Biopharmaceutical support in formulation



• Development

The book is ideal for practitioners working in the pharmaceutical arena—including R&D scientists, technicians, and managers—as well as for undergraduate and postgraduate courses in industrial pharmacy and pharmaceutical technology.

Table of contents

• Cover
• Half Title
• Series Page
• For information on volumes 1–149 in the Drugs and Pharmaceutical Science Series, please visit www.informahealthcare.com
• Title Page
• Copyright Page
• Preface
• Table of Contents
• Contributors
• 1 Introduction and Perspective
• 2 Aiding Candidate Drug Selection: Introduction and Objectives
• 3 Preformulation Investigations using Small Amounts of Compound as an Aid to Candidate Drug Selection and Early Development
• 4 Biopharmaceutical Support in Candidate Drug Selection
• 5 Early Drug Development: Product Design
• 6 Preformulation as an Aid to Product Design in Early Drug Development
• 7 Biopharmaceutical Support in Formulation Development
• 8 Product Optimization
• 9 Parenteral Dosage Forms
• 10 Inhalation Dosage Forms
• 11 Oral Solid Dosage Forms
• 12 Ophthalmic Dosage Forms
• 13 Aqueous Nasal Dosage Forms
• 14 Topical and Transdermal Delivery
• Index