The World Stroke Organization reports that "stroke has already reached epidemic proportions. Globally1 in 4 adults over the age of 25 will have a stroke in their lifetime. 12.2 million people worldwide will have their first stroke this year, and 6.5 million will die as a result." Ischemic strokes are the most common type of stroke, with about 87% of all strokes being ischemic strokes.

This new volume addresses this epidemic by presenting detailed studies on ischemic injury, with emphasis on the molecular-level mechanisms and the role of signaling pathways in the body, their structure, and their mechanism of action. The book focuses on molecular pharmacology plans and explains the new areas of research on the discovery of therapeutic molecules that can be used for combating this life-threatening disease. The authors discuss stroke occurrence at different stages of life as well as sex-based differences in its treatment. They cover aspects of the clinical treatment and diagnosis of patients with cardiovascular events, including in-depth information on the prevention, evaluation, therapy selection, result projection, and long-term course of the disease in affected patients. They also detail the involvement of platelets, neurotransmitters, renin-angiotensin-aldosterone system, and vitamin D in ischemic injury.

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription.

At the moment all of our mobile-responsive ePub books are available to download via the app. Most of our PDFs are also available to download and we're working on making the final remaining ones downloadable now. Learn more here.

Perlego offers two plans: Essential and Complete

Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.

Both plans are available with monthly, semester, or annual billing cycles.

We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.

Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.

Yes! You can use the Perlego app on both iOS or Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.

Yes, you can access Ischemic Injury by Thakur Gurjeet Singh, Heena Khan, Thakur Gurjeet Singh,Heena Khan in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Medicine

Subtopic

Pharmacology

Cover Page
Half Title Page
Title Page
Copyright Page
About the Editors
Contents
Contributors
Abbreviations
Preface
Chapter 1 Stroke Insight
Chapter 2 Myocardial Ischemic-Reperfusion Injury
Chapter 3 Preclinical and Clinical Aspects of I/R Injuries
Chapter 4 Molecular Aspects of Ischemic Reperfusion Injury
Chapter 5 Role of Mitochondria in Ischemic-Reperfusion Injury
Chapter 6 Stroke and its Effects in Daily Life
Chapter 7 Etiopathogenesis and Molecular Targets in Cerebral Ischemia: Current Understanding of Stroke and Therapeutic Approaches
Chapter 8 Expatiating the Pivotal Role of Matrix Metalloproteinases and Blood-Brain Barrier Disruption in Ischemic Stroke: Molecular Insights and Therapeutic Targets
Chapter 9 Acute Ischemic Stroke in COVID-19 Patients
Chapter 10 Neurotransmission Imbalance: A Major Factor in the Worsening of Ischemic Injury
Chapter 11 Role of the Renin-Angiotensin-Aldosterone System (RAAS) in Amelioration of Stroke Pathophysiology
Chapter 12 Stroke and Diabetes in Vitamin D Deficiency: Prospects of Intertwined Pathobiologies
Chapter 13 Remote Ischemic Postconditioning: An Overview
Chapter 14 Sex-Based Differences in Acute Kidney Injury: Lessons from Renal Ischemia-Reperfusion Injury Model in Rodents
Chapter 15 Critical Overview of Conditioning Techniques and Their Current Status in the Treatment of Myocardial Ischemia-Reperfusion Injury
Chapter 16 Involvement of Platelets in Myocardial Ischemia and Reperfusion Injury
Chapter 17 Recent Advancements in Strategies for the Treatment of Cerebral Ischemia
Chapter 18 Recent Therapeutic Approaches Toward the Management of Ischemic Heart Disease
Chapter 19 Nanotechnology-Assisted Treatment for Ischemic Heart Disease and Related Recent Patents
Chapter 20 Major Risk Factors Involved in the Pathobiology of Ischemic Brain and Heart Disorders
Chapter 21 Modulating Mitogen-Activated Protein Kinase (MAPK) Downstream Signaling Pathways in Cerebral Ischemic Hemorrhages
Chapter 22 Implication of Mitogen-Activated Protein Kinase (MAPK) in Cerebral Stroke
Chapter 23 Regulation of JNK Signaling Pathway in Ischemia/Reperfusion Injury
Chapter 24 Role of Glycogen Synthase Kinase-3β (Gsk-3β) in Intracranial Hemorrhage
Chapter 25 Role of GSK-3 Inhibition in Modulating the Pathology of Stroke
Chapter 26 Regulation of Nrf-2 Signaling Pathway in Ischemia/Reperfusion Injury
Chapter 27 Regulation of PI3K-Akt Signaling Pathway in Ischemia/Reperfusion Injury
Chapter 28 COVID-19 and Ischemic Stroke: Advancements and Challenges
Index

About this book

Frequently asked questions

Information

Table of contents