Pathophysiology, Risk Factors, and Management of Chronic Heart Failure

Ram B. Singh, Jan Fedacko, Krasimira Hristova, Galal Eldin Nagib Elkilany, Ram B. Singh, Jan Fedacko, Krasimira Hristova, Galal Eldin Nagib Elkilany

• Publisher: Academic Press
• Year: 2024
• Print ISBN:
  9780128229729
• eBook ISBN:
  9780128231111
• Topic: Biological Sciences
• Subtopic: Cardiology
• Index: Biological Sciences

Chronic Heart Failure: Pathophysiology, Risk factors, and Mechanisms is the first of two separate but closely related volumes which aim to provide an inclusive overview on Chronic Heart Failure (CHF). This first volume is focused on the epidemiology, classification, molecular mechanisms, pathophysiology, causes, identification and interactions of heart failure. It will explain the uncertainties and issues in Heart Failure by helping readers understand the physiopathology of CHF in the light of behavioural risk factors. 2D and 3D speckle tracking echocardiography have been used to quantify regional alterations of longitudinal strain and area strain, through their polar projection, which allows a further evaluation of both the site and extent of myocardial damage. The analysis of strain can identify subclinical cardiac failure (myocyte remodelling) which is a major issue in CHF. Myocardial Strain, measure by speckle tracking echocardiography, is frequently attenuated in these conditions and can be utilized for the evaluation of disease progression and the effect of therapeutic interventions as well as prevention because it could be a manifestation of behavioural risk factors. These 2 separate volumes serves as essential references to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agent, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF. - Includes a number new and controversial topics: Roles of both behavioural and nutritional risk factors in CHF; considering behavioural intervention which may change the remodelling, as well as nutrient supplementation or change of diet in preventing CHF or converting resistant HF in to HF responding to therapy; Evidence-based knowledge on CHF, with an emphasis on viewing CHF as a disease of the brain and contribution from other systems; Pre–Heart failure which can be prevented to restore normal cardiomyocyte function; Pathogenesis of HF in chronic kidney disease; 2D and 3D speckle tracking echocardiography - Includes never-published tables and figures to aid understanding of the topics - Contributions from international leading experts in the field, written with the aim of serving both researchers and practicing clinicians

Table of contents

• Pathophysiology, Risk Factors, and Management of Chronic Heart Failure
• Chapter 1 History of medicine from ancient times to present
• Chapter 2 Epidemiology and mortality due to heart failure
• Chapter 3 Behavioral risk factors of chronic heart failure
• Chapter 4 Nutritional factors in the pathogenesis of heart failure: a review
• Chapter 5 Evolution of the natural history of myocardial twist and diastolic dysfunction as cardiac dysfunction
• Chapter 6 Preheart failure: a stage of chronic heart failure
• Chapter 7 Classification of chronic heart failure as per New York Heart Association
• Chapter 8 Molecular and cellular biology and genetic factors in chronic heart failure
• Chapter 9 Pathophysiology of chronic heart failure
• Chapter 10 Circadian dysfunction in the pathogenesis of heart failure
• Chapter 11 Cardiac remodeling in chronic heart failure: pathophysiological implications
• Chapter 12 Pathophysiology of abnormalities involving calcium signalling during cardiac muscle contraction
• Chapter 13 Abnormalities in the cardiac relaxation
• Chapter 14 Renal dysfunction and heart disease: elucidating the cardiorenal relationship approaches leading to heart failure
• Chapter 15 Role of brain with reference to autonomic nervous system dysfunctions, as predisposing factor of chronic heart failure?
• Chapter 16 Heart failure in chronic kidney disease
• Chapter 17 Role of noninvasive imaging with reference to speckle-tracking echocardiography
• Chapter 18 Advances in echocardiographic imaging in chronic heart failure
• Chapter 19 Congenital heart diseases
• Chapter 20 Cardiac magnetic resonance imaging in chronic heart failure
• Chapter 21 Role of pulmonary ultrasound in heart failure
• Chapter 22 Physical training in heart failure
• Chapter 23 Nutritional management in heart failure
• Chapter 24 Management of arrhythmia in chronic heart failure
• Chapter 25 Ivabradine: sinus rhythm control in heart failure
• Chapter 26 Guidelines for the management of chronic heart failure
• Chapter 27 Renin–angiotensin–aldosterone system inhibitors in the heart failure management
• Chapter 28 Beta-blocker therapy among patients with heart failure
• Chapter 29 Treatment of heart failure using angiotensin receptor neprilysin inhibitor
• Chapter 30 Effects of mineralocorticoid antagonist therapy in heart failure
• Chapter 31 Sodium glucose transporters inhibitors in the management of heart failure
• Chapter 32 Role of vasodilators and digitalis in heart failure
• Chapter 33 Vericiguat as part of a multidrug approach following a worsening heart failure event
• Index
• Index - Continued