Spirooxindole

Chemistry, Synthesis, Characterization and Biological Significance

Gautam Patel, Vraj R. Shah, Tuan Anh Nguyen, Kalim Deshmukh, Gautam Patel, Vraj R. Shah, Tuan Anh Nguyen, Kalim Deshmukh

• Publisher: Elsevier
• Year: 2024
• Print ISBN:
  9780443223242
• eBook ISBN:
  9780443223259
• Topic: Technology & Engineering
• Subtopic: Materials Science
• Index: Technology & Engineering

Modern advances in organic synthesis require compouds having attractive properties with high percentage of yield. Spirooxindole examines the current state of the art, recent progress and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in vaious fields, including chemical and pharma industries, and in clinical research. This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences.The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book. - Consolidates information on each aspect of this novel compound and its applications in various fields, covering the entire spectrum of up-to-date literature citations, current market, and patents - Provides a comprehensive, in-depth description of spirooxindole derivatives as well as multipurpose scaffolds - Highlights green synthesis and nanocatalysis - Describes in-depth various medicinal applications - Covers both synthesis and applications

Table of contents

• Spirooxindole
• Chapter 1 Synthesis of spirooxindoles by [3+2] cycloadditions
• Chapter 2 Synthesis of spirooxindoles under ultrasonication
• Chapter 3 Organocatalyzed cycloaddition of N-2,2,2-trifluoroethylisatin ketimines for synthesis of CF3-containing spirooxindoles
• Chapter 4 Regio- and stereoselective synthesis of spirooxindole scaffold
• Chapter 5 Synthesis of spiroheterocyclic compounds by using isatin
• Chapter 6 Synthesis of highly functionalized spirooxindole derivatives via multicomponent [3+2] cycloaddition reactions
• Chapter 7 Organocatalyzed enantioselective synthesis of spirooxindole scaffolds
• Chapter 8 Synthesis of spirooxindoles and its derivatives using green and nanotechnology
• Chapter 9 Recent strategies in the synthesis of spirooxindole scaffolds (stereoselective synthesis)
• Chapter 10 Characterization techniques for synthesized spirooxindole scaffold
• Chapter 11 Stereoselective synthesis of spirooxindole scaffold
• Chapter 12 Synthesis of hybrid spirooxindoles
• Chapter 13 Anticancer properties of spirooxindole derivatives
• Chapter 14 Medicinal application of spirooxindole and its derivatives: an introduction
• Chapter 15 Spirooxindole derivatives as an anticancer agents: Synthetic developments, structure–activity relationship, and biological applications
• Chapter 16 Spirooxindole derivatives as an anticancer agent
• Chapter 17 Spirooxindole derivatives as kinase-based anticancer agents
• Chapter 18 Spirooxindole derivatives as antioxidant agents
• Chapter 19 Spirooxindole derivatives as promising antiviral agents: Structure–activity relationship studies and biological perspectives
• Chapter 20 Spirooxindole derivatives as an agrochemical
• Chapter 21 Other medicinal applications
• Chapter 22 Spirooxindole derivatives as antibacterial agents
• Chapter 23 Medicinal applications of spirooxindole and its derivatives
• Chapter 24 Anticancer effect of spirooxindole derivatives
• Chapter 25 Anticancer potential of spirooxindole derivatives
• Index